Anti-Claudin 10 CLDN10 Antibody

Product Name

Anti-Claudin 10 CLDN10 Antibody

View all Claudin 10 Antibodies

SKU/Catalog Number

A10653

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-Claudin 10 CLDN10 Antibody (Catalog # A10653). Tested in WB applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Claudin 10 CLDN10 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A10653)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human Claudin 10.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A10653 is reactive to CLDN10 in Human, Mouse

Applications

A10653 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

24.488kDa

Background of Claudin 10

Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. May form permselective paracellular pores; isoform 1 appears to create pores preferentially permeable to cations and isoform 2 for anions. Plays a key role in controlling cation selectivity and transport in the thick ascending limb (TAL) of Henle's loop in kidney.

Siu Tim Cheung, Clin. Cancer Res., Jan 2005; 11: 551 - 556.
Hiroki Fujita, J. Histochem. Cytochem., Aug 2006; 54: 933 - 944.
Christina M. Van Itallie, Am J Physiol Renal Physiol, Dec 2006; 291: F1288 - F1299.
Anne Florin, Endocrinology, Mar 2005; 146: 153

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000

Validation Images & Assay Conditions

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Western blot analysis of extracts from A549 cells (Lane 2), using Claudin 10 antiobdy A10653. The lane on the left is treated with synthesized peptide.

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Western blot analysis of extracts from LOVO cells, using Claudin 10 antibody A10653.

Gene/Protein Information For CLDN10 (Source: Uniprot.org, NCBI)

Alternative Names

claudin 10; claudin-10; CPETRL3; OSP-L; OSP-like protein CLDN10 CPETRL3, HELIX, OSP-L, OSPL claudin 10 claudin-10|OSP-like protein|oligodendrocyte-specific protein-like

For more info on CLDN10, check out the CLDN10 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CLDN10: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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