Anti-Collagen, Type IV COL4A1 Antibody (Monoclonal, COL-94)

Product Name

Anti-Collagen, Type IV COL4A1 Antibody (Monoclonal, COL-94)

View all Collagen IV alpha 1 Antibodies

SKU/Catalog Number

MA1030

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Collagen, Type IV COL4A1 Antibody (Monoclonal, COL-94) catalog # MA1030. Tested in IHC applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Collagen, Type IV COL4A1 Antibody (Monoclonal, COL-94) (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1030)

Host

Mouse

Contents

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Clonality

Monoclonal

Clone Number

COL-94

Isotype

Mouse IgG1

Immunogen

Human collagen type IV.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

MA1030 is reactive to COL4A1 in Human

Applications

MA1030 is guaranteed for IHC Boster Guarantee

Observed Molecular Weight

49 kDa

Calculated molecular weight

160.611kDa

Background of Collagen IV alpha 1

Collagen IV is comprised of a third chain (alpha-3) together with the 2 classical ones, alpha-1 and alpha-2. COL4A3 gene is localized to 2q36-q37 by analysis of somatic cell hybrids and by in situ hybridization. The alpha-3 chain of type IV collagen induces autoimmune Goodpasture syndrome. Mutations in the COL4A4 and COL4A3 genes cause familial benign hematuria.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat
Immunohistochemistry (Frozen Section), 0.5-1μg/ml, Human

Validation Images & Assay Conditions

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Anti-Collagen, Type IV antibody (monoclonal), MA1030, IHC(P)
IHC(P): Human Mammary Cancer Tissue

Gene/Protein Information For COL4A1 (Source: Uniprot.org, NCBI)

Alternative Names

alpha-1 chain; Arresten; COL4A1 NC1 domain; COL4A1; collagen alpha-1(IV) chain; Collagen IV alpha 1; collagen IV, alpha-1 polypeptide; collagen, type IV, alpha 1; Collagen-4; EC 3.4.23; EC 6.3.1.2 COL4A1 BSVD, BSVD1s, PADMAL, RATOR, COL4A1 collagen type IV alpha 1 chain collagen alpha-1(IV) chain|COL4A1 NC1 domain|arresten|collagen IV, alpha-1 polypeptide|collagen of basement membrane, alpha-1 chain

For more info on COL4A1, check out the COL4A1 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for COL4A1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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