Product Info Summary
SKU: | A09550-1 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-CTRP1 C1QTNF1 Antibody
View all C1qTNF1/CTRP1 Antibodies
SKU/Catalog Number
A09550-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-CTRP1 C1QTNF1 Antibody (Catalog # A09550-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
CTRP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-CTRP1 C1QTNF1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09550-1)
Host
Rabbit
Contents
CTRP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
SK7
Isotype
IgG
Immunogen
CTRP1 (NT) antibody was raised against a 15 amino acid synthetic peptide from near the amino-terminus of human CTRP1. The immunogen is located within amino acids 40 - 90 of CTRP1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
These proteins are often highly modified post-translationally and migrate in SDS-PAGE at positions other than their predicted size.
Reactive Species
A09550-1 is reactive to C1qtnf1 in Human, Mouse, Rat
Applications
A09550-1 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
32.009kDa
Background of C1qTNF1/CTRP1
Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. In obese (ob/ob) mice, RT-PCR analysis showed that mCTRP1 transcripts are seen at substantially higher levels in adipose tissues compared to those of normal mice.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
CTRP1 antibody can be used for the detection of CTRP1 by Western blot at 1 and 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of CTRP1 in human kidney cell lysate with CTRP1 antibody at (A) 1 and (B) 2 μg/mL.
Click image to see more details
Immunohistochemistry of CTRP1 in human kidney tissue with CTRP1 antibody at 10 μg/mL.
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Immunofluorescence of CTRP1 in Human Kidney cells with CTRP1 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For C1qtnf1 (Source: Uniprot.org, NCBI)
Gene Name
C1qtnf1
Full Name
Complement C1q tumor necrosis factor-related protein 1
Weight
32.009kDa
Alternative Names
C1q and tumor necrosis factor related protein 1; C1qTNF1; CTRP1; CTRP1G protein-coupled receptor-interacting protein; FLJ90694; G protein coupled receptor interacting protein; GIPcomplement C1q tumor necrosis factor-related protein 1; ZSIG37 C1qtnf1|1600017K21Rik, Adip, CTR, CTRP1, Zsig37|C1q and tumor necrosis factor related protein 1|complement C1q tumor necrosis factor-related protein 1|adiponectin p|putative secreted protein ZSIG37
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on C1qtnf1, check out the C1qtnf1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for C1qtnf1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CTRP1 C1QTNF1 Antibody (A09550-1)
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