Anti-CYP3A4/5 (F386) Antibody

CYP3A4 antibody

Boster Bio Anti-CYP3A4/5 (F386) Antibody catalog # A00339-1. Tested in WB,IHC,IF applications. This antibody reacts with Human,Mouse,Rat.

Product Info Summary

SKU: A00339-1
Size: 100ul
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IF, IHC, WB

Product Name

Anti-CYP3A4/5 (F386) Antibody

View all CYP3A4 Antibodies

SKU/Catalog Number

A00339-1

Size

100ul

Form

Liquid

Description

Boster Bio Anti-CYP3A4/5 (F386) Antibody catalog # A00339-1. Tested in WB,IHC,IF applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-CYP3A4/5 (F386) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00339-1)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human Cytochrome P450 3A4.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A00339-1 is reactive to CYP3A4 in Human, Mouse, Rat

Applications

A00339-1 is guaranteed for IF, IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

57.343kDa

Background of CYP3A4

Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,8-cineole 2-exo-monooxygenase. The enzyme also hydroxylates etoposide.

Vuoristo M.M., J. Biol. Chem. 270:22873-22881(1995).
Mungall A.J., Nature 425:805-811(2003).
Lui V.C., Genomics 32:401-412(1996).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:1000
IHC: 1:50-1:200
IF: 1:50-1:200

Validation Images & Assay Conditions

Gene/Protein Information For CYP3A4 (Source: Uniprot.org, NCBI)

Gene Name

CYP3A4

Full Name

Cytochrome P450 3A4

Weight

57.343kDa

Superfamily

cytochrome P450 family

Alternative Names

Albendazole Monooxygenase; Albendazole Sulfoxidase; CP33; CP34; CYP3A; CYP3A3; CYP3A4; CYPIIIA3; CYPIIIA4; Cytochrome P450 3A3; cytochrome P450 3A4; Cytochrome P450 HLp; Cytochrome P450 NF-25; cytochrome P450, family 3, subfamily A, polypeptide 4; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4; Cytochrome P450-PCN1; EC 1.14.13.32; EC 1.14.13.67; EC 1.14.13.97; EC 1.14.14.1; glucocorticoid-inducible P450; HLP; MGC126680; NF-25; Nifedipine oxidase; P450C3; P450-III, steroid inducible; P450PCN1; Quinine 3- CYP3A4 CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1, VDDR3 cytochrome P450 family 3 subfamily A member 4 cytochrome P450 3A4|1,4-cineole 2-exo-monooxygenase|1,8-cineole 2-exo-monooxygenase|P450-III, steroid inducible|albendazole monooxygenase (sulfoxide-forming)|albendazole sulfoxidase|cholesterol 25-hydroxylase|cytochrome P450 3A3|cytochrome P450 HLp|cytochrome P450 NF-25|cytochrome P450, family 3, subfamily A, polypeptide 4|cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3|cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4|cytochrome P450-PCN1|glucocorticoid-inducible P450|nifedipine oxidase|quinine 3-monooxygenase|taurochenodeoxycholate 6-alpha-hydroxylase

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CYP3A4, check out the CYP3A4 Infographic

CYP3A4 infographic

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In this infographic, you will see the following information for CYP3A4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A00339-1-100ul

100ul

$405

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