Anti-D6/ACKR2 Antibody Picoband™

CC Chemokine Receptor D6 antibody

Boster Bio Anti-D6/ACKR2 Antibody Picoband™ catalog # A05491-2. Tested in ELISA, IHC, WB applications. This antibody reacts with Human.

Product Info Summary

SKU: A05491-2
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: ELISA, IHC, WB

Product Name

Anti-D6/ACKR2 Antibody Picoband™

View all CC Chemokine Receptor D6 Antibodies

SKU/Catalog Number

A05491-2

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-D6/ACKR2 Antibody Picoband™ catalog # A05491-2. Tested in ELISA, IHC, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-D6/ACKR2 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05491-2)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human D6/ACKR2 recombinant protein (Position: M138-A384).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A05491-2 is reactive to ACKR2 in Human

Applications

A05491-2 is guaranteed for ELISA, IHC, WB Boster Guarantee

Background of CC Chemokine Receptor D6

This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml
Direct ELISA, 0.1-0.5μg/ml

Validation Images & Assay Conditions

Gene/Protein Information For ACKR2 (Source: Uniprot.org, NCBI)

Uniprot ID

O00590

Gene ID

1238

Gene Name

ACKR2

Full Name

Atypical chemokine receptor 2

Weight

43.443kDa

Superfamily

G-protein coupled receptor 1 family

Alternative Names

ACKR2; C-C chemokine receptor D6; CCBP2; CCR10CCR9D6CC-chemokine-binding receptor JAB61; chemokine (C-C) receptor 9; chemokine binding protein 2; Chemokine receptor CCR-10; Chemokine receptor CCR-9; chemokine receptor D6; chemokine-binding protein 2; Chemokine-binding protein D6; CMKBR9; CMKBR9chemokine (C-C motif) receptor 9; D6; hD6; MGC126678; MGC138250 ACKR2 CCBP2, CCR10, CCR9, CMKBR9, D6, hD6 atypical chemokine receptor 2 atypical chemokine receptor 2|C-C chemokine receptor D6|CC-chemokine-binding receptor JAB61|chemokine (C-C motif) receptor 9|chemokine (C-C) receptor 9|chemokine receptor CCR-10|chemokine receptor CCR-9|chemokine receptor D6|chemokine-binding protein 2|chemokine-binding protein D6

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on ACKR2, check out the ACKR2 Infographic

ACKR2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for ACKR2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]

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1 Customer Q&As for Anti-D6/ACKR2 Antibody Picoband™

Question

We are currently using anti-D6/ACKR2 antibody A05491-2 for human tissue, and we are content with the IHC-P results. The species of reactivity given in the datasheet says human. Is it likely that the antibody can work on dog tissues as well?

G. Zhao

Verified customer

Asked: 2018-02-21

Answer

The anti-D6/ACKR2 antibody (A05491-2) has not been tested for cross reactivity specifically with dog tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in dog you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2018-02-21

Size

Conjugation

Total: $315

SKU:A05491-2

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Ships directly to USA and Canada. For other regions, visit our distributors page

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A05491-2
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$315.00

$50 fee for conjugation. Antibody size is reduced to 50ug.

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