Click image to see more details
Product Info Summary
| SKU: | A09406-1 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Rat |
| Host: | Rabbit |
| Application: | WB |
Customers Who Bought This Also Bought
Product info
Product Name
Anti-DC-LAMP (E305) LAMP3 Antibody
SKU/Catalog Number
A09406-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-DC-LAMP (E305) LAMP3 Antibody catalog # A09406-1. Tested in WB applications. This antibody reacts with Human,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-DC-LAMP (E305) LAMP3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09406-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
Synthetic peptide, corresponding to amino acids 275-335 of Human DC-LAMP.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A09406-1 is reactive to LAMP3 in Human, Rat
Applications
A09406-1 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
44.346kDa
Background of DC-LAMP
Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38L.
Florindo C.S., Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Devroe E., J. Biol. Chem. 279:24444-24451(2004).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Innovating Scientists Reward
If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.
Submit A Review
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:1000-1:2000
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-DC-LAMP (E305) LAMP3 Antibody A09406-1
Western blot (WB) analysis of DC-LAMP (E305) polyclonal antibody at 1:1000 dilutionLane1:HCT116 whole cell lysate(30ug)
Lane2:The Thymus tissue lysate of Rat(40ug)
Lane3:A549 whole cell lysate(40ug)
Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For LAMP3 (Source: Uniprot.org, NCBI)
Gene Name
LAMP3
Full Name
Lysosome-associated membrane glycoprotein 3
Weight
44.346kDa
Superfamily
LAMP family
Alternative Names
CD208 antigen; CD208; DCLAMP; DC-LAMP; DCLAMPDC-lysosome-associated membrane glycoprotein; LAMP; LAMP3; LAMP-3; lysosomal-associated membrane protein 3DC LAMP; lysosome-associated membrane glycoprotein 3; Protein TSC403; TSC403; TSC403CD208 LAMP3 CD208, DC LAMP, DC-LAMP, DCLAMP, LAMP, LAMP-3, TSC403 lysosomal associated membrane protein 3 lysosome-associated membrane glycoprotein 3|DC-lysosome-associated membrane glycoprotein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on LAMP3, check out the LAMP3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for LAMP3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-DC-LAMP (E305) LAMP3 Antibody (A09406-1)
Hello CJ!
No publications found for A09406-1
*Do you have publications using this product? Share with us and receive a reward. Ask us for more details.
Recommended Resources
Here are featured tools and databases that you might find useful.
- Boster's Pathways Library
- Protein Databases
- Bioscience Research Protocol Resources
- Data Processing & Analysis Software
- Photo Editing Software
- Scientific Literature Resources
- Research Paper Management Tools
- Molecular Biology Software
- Primer Design Tools
- Bioinformatics Tools
- Phylogenetic Tree Analysis
Customer Reviews
Have you used Anti-DC-LAMP (E305) LAMP3 Antibody?
Submit a review and receive an Amazon gift card.
- $30 for a review with an image
Be the first to review Anti-DC-LAMP (E305) LAMP3 Antibody
*The first user to submit a review for a product is eligible for Boster's Innovating Scientists Reward, which gives product credits. This is in addition to the gift card reward.
Customer Q&As
Have a question?
Find answers in Q&As, reviews.
Can't find your answer?
Submit your question
