Anti-DDC Antibody

Dopa Decarboxylase/DDC antibody

Boster Bio Anti-DDC Antibody (Catalog # A01374). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A01374
Size: 0.1 mg
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, IF, IHC-P, WB

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Product Name

Anti-DDC Antibody

View all Dopa Decarboxylase/DDC Antibodies

SKU/Catalog Number

A01374

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-DDC Antibody (Catalog # A01374). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

DDC antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Cite This Product

Anti-DDC Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01374)

Host

Rabbit

Contents

DDC Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

DDC antibody was raised against a 14 amino acid peptide near the carboxy terminus of human DDC. The immunogen is located within amino acids 390 - 440 of DDC .

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

DDC antibody is human, mouse and rat reactive.

Reactive Species

A01374 is reactive to DDC in Human, Mouse, Rat

Applications

A01374 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Background of Dopa Decarboxylase/DDC

DOPA decarboxylase (DDC) belongs to the group II decarboxylase family of proteins (1). It is an important protein in the catecholamine biosynthesis pathway. DDC catalyzes the second reaction in the biosynthesis of catecholamines, trace amines and serotonin (1,2). It can form a homodimer and is expressed in the central nervous system (2). DDC can be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease, neuroendocrine tumors and drug abuse (3,4). Defects in DDC gene may cause the autosomal recessive disorder AADC deficiency (4).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

DDC antibody can be used for detection of DDC by Western blot at 1 - 2 μg/mL. Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Validation Images & Assay Conditions

Gene/Protein Information For DDC (Source: Uniprot.org, NCBI)

Uniprot ID

P20711

Gene ID

1644

Gene Name

DDC

Full Name

Aromatic-L-amino-acid decarboxylase

Weight

53.926kDa

Superfamily

group II decarboxylase family

Alternative Names

AADC; AADCaromatic-L-amino-acid decarboxylase; DDC; dopa decarboxylase (aromatic L-amino acid decarboxylase); Dopa Decarboxylase; EC 4.1.1; EC 4.1.1.28 DDC AADC dopa decarboxylase aromatic-L-amino-acid decarboxylase|dopa decarboxylase (aromatic L-amino acid decarboxylase)

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on DDC, check out the DDC Infographic

DDC infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for DDC: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]

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Size

Total: $404

SKU:A01374

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Ships directly to USA and Canada. For other regions, visit our distributors page

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A01374
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$404.00

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