Click image to see more details
Product Info Summary
| SKU: | M11863 |
|---|---|
| Size: | 100 µg |
| Reactive Species: | Human, Mouse |
| Host: | Mouse |
| Application: | IHC, WB, FACS |
Customers Who Bought This Also Bought
Product info
Product Name
Anti-Dectin-2 CLEC6A Antibody (Monoclonal, ABM2H28)
View all Dectin-2/CLEC6A Antibodies
SKU/Catalog Number
M11863
Size
100 µg
Form
Liquid
Description
Boster Bio Anti-Dectin-2 CLEC6A Antibody (Monoclonal, ABM2H28) (Catalog# M11863). Tested in IHC, FACS, WB application(s). This antibody reacts with Mouse, Human.
Storage & Handling
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Cite This Product
Anti-Dectin-2 CLEC6A Antibody (Monoclonal, ABM2H28) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M11863)
Host
Mouse
Contents
100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide.
Clonality
Monoclonal
Clone Number
ABM2H28
Isotype
IgG2a Kappa
Immunogen
A partial length recombinant Dectin-2 protein (amino acids 70-230)
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Does not cross-react with primate, avian or amphibian GR.
Reactive Species
M11863 is reactive to CLEC6A in Human, Mouse
Applications
M11863 is guaranteed for IHC, WB, FACS Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
23.998kDa
Background of Dectin-2/CLEC6A
The regions of relatively constant sequence beyond the variable regions of immunoglobulins are termed constant regions (C regions) and are present in both the heavy and light chains. With very few exceptions, the sites of attachment for carbohydrates on immunoglobulins are located in these C regions. These regions also function to hold the variable regions together by using the disulfide bond between them. The C regions facilitate interaction with the antigen by increasing the maximum rotation of the immunoglobulin arms. Reportedly, a large population of patients with recurrent respiratory tract infection has low IgG4 concentrations. IgG4-related sclerosing disease has been recognized as a systemic disease entity characterized by an elevated serum IgG4 level, sclerosing fibrosis, and diffuse lymphoplasmacytic infiltration with the presence of many IgG4-positive plasma cells.IgG4 is overexpressed in inflammatory pseudotumor (IPT) and under expressed in inflammatory myofibroblastic tumor (IMT). In pulmonary nodular lymphoid hyperplasia (PNLH), there are an increased number of IgG4+ plasma cells.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Innovating Scientists Reward
If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.
Submit A Review
Assay dilution & Images
Reconsitution
Reconstitute with distilled water.
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blot: 2-4 µg/ml
FACS analysis: 0.5 µg/10^6 cells
IHC: 5 µg/ml
Validation Images & Assay Conditions
Click image to see more details
Intracellular flow analysis of Dectin-2 in human PBMC (Lymphocytes) using 0.5 &mu
Click image to see more details
Immunohistochemical analysis of Dectin-2 in Renal Cell Carcinoma using Dectin-2 antibody (Clone: ABM2H28) at 5 &mu
Click image to see more details
Western blot analysis of Dectin 2 Anti-Dectin 2 antibody (Clone: ABM2H28) was used at 2 &mu
Protein Target Info & Infographic
Gene/Protein Information For CLEC6A (Source: Uniprot.org, NCBI)
Gene Name
CLEC6A
Full Name
C-type lectin domain family 6 member A
Weight
23.998kDa
Alternative Names
CLEC4N; CLEC6A; CLECSF10; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 10; C-type lectin domain family 6 member A; C-type lectin domain family 6, member A; C-type lectin superfamily member 10; DC-associated C-type lectin 2; dectin 2; Dectin2; Dectin-2; Dendritic cell-associated C-type lectin 2 CLEC6A CLEC4N, CLECSF10, dectin-2 C-type lectin domain containing 6A C-type lectin domain family 6 member A|C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 10|C-type lectin superfamily member 10|DC-associated C-type lectin 2|dectin 2|dendritic cell-associated C-type lectin 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CLEC6A, check out the CLEC6A Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CLEC6A: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Dectin-2 CLEC6A Antibody (Monoclonal, ABM2H28) (M11863)
Hello CJ!
No publications found for M11863
*Do you have publications using this product? Share with us and receive a reward. Ask us for more details.
Recommended Resources
Here are featured tools and databases that you might find useful.
- Boster's Pathways Library
- Protein Databases
- Bioscience Research Protocol Resources
- Data Processing & Analysis Software
- Photo Editing Software
- Scientific Literature Resources
- Research Paper Management Tools
- Molecular Biology Software
- Primer Design Tools
- Bioinformatics Tools
- Phylogenetic Tree Analysis
Customer Reviews
Have you used Anti-Dectin-2 CLEC6A Antibody (Monoclonal, ABM2H28)?
Submit a review and receive an Amazon gift card.
- $30 for a review with an image
Be the first to review Anti-Dectin-2 CLEC6A Antibody (Monoclonal, ABM2H28)
*The first user to submit a review for a product is eligible for Boster's Innovating Scientists Reward, which gives product credits. This is in addition to the gift card reward.
Customer Q&As
Have a question?
Find answers in Q&As, reviews.
Can't find your answer?
Submit your question
1 Customer Q&As for Anti-Dectin-2 CLEC6A Antibody (Monoclonal, ABM2H28)
Question
We are currently using anti-Dectin-2 antibody (Monoclonal, ABM2H28) M11863 for mouse tissue, and we are happy with the IHC results. The species of reactivity given in the datasheet says human, mouse. Is it possible that the antibody can work on zebrafish tissues as well?
Verified Customer
Verified customer
Asked: 2019-09-12
Answer
The anti-Dectin-2 antibody (Monoclonal, ABM2H28) (M11863) has not been tested for cross reactivity specifically with zebrafish tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in zebrafish you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2019-09-12
