Anti-DOCK180/DOCK1 Antibody Picoband™

DOCK1 antibody

Boster Bio Anti-DOCK180/DOCK1 Antibody Picoband™ catalog # A03440-2. Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human.

Product Info Summary

SKU: A03440-2
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: ELISA, Flow Cytometry, IF, IHC, WB

Product Name

Anti-DOCK180/DOCK1 Antibody Picoband™

View all DOCK1 Antibodies

SKU/Catalog Number

A03440-2

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-DOCK180/DOCK1 Antibody Picoband™ catalog # A03440-2. Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human.

Storage & Handling

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Cite This Product

Anti-DOCK180/DOCK1 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03440-2)

Host

Rabbit

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human DOCK180/DOCK1 recombinant protein (Position: S100-T1732).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A03440-2 is reactive to DOCK1 in Human

Applications

A03440-2 is guaranteed for ELISA, Flow Cytometry, IF, IHC, WB Boster Guarantee

Background of DOCK1

Dock180, (Dedicator of cytokinesis) also known as DOCK1, is a large (~180 kDa) protein involved in intracellular signalling networks. This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Reconsitution

Adding 0.2 ml of distilled water will yield a concentration of 500 µg/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Western blot, 0.25-0.5 µg/ml, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 µg/ml, Human
Immunofluorescence, 5 μg/ml, Humann
Flow Cytometry, 1-3 µg/1x106 cells, Human
Direct ELISA, 0.1-0.5 µg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For DOCK1 (Source: Uniprot.org, NCBI)

Uniprot ID

Q14185

Gene ID

1793

Gene Name

DOCK1

Full Name

Dedicator of cytokinesis protein 1

Weight

215.346kDa

Superfamily

DOCK family

Alternative Names

180 kDa protein downstream of CRK; ced5; dedicator of cytokinesis 1; dedicator of cyto-kinesis 1; DOCK1; DOCK180; DOCK180dedicator of cytokinesis protein 1; DOwnstream of CrK DOCK1 DOCK180, ced5 dedicator of cytokinesis 1 dedicator of cytokinesis protein 1|180 kDa protein downstream of CRK|DOwnstream of CrK

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on DOCK1, check out the DOCK1 Infographic

DOCK1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for DOCK1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]

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Size

Conjugation

Total: $315

SKU:A03440-2

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Ships directly to USA and Canada. For other regions, visit our distributors page

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A03440-2
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$315.00

$50 fee for conjugation. Antibody size is reduced to 50ug.

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