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Product Info Summary
| SKU: | A03714 |
|---|---|
| Size: | 100 µl |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-ELF4/Mef Antibody
SKU/Catalog Number
A03714
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-ELF4/Mef Antibody (Catalog # A03714). Tested in WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-ELF4/Mef Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03714)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human ELF4.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A03714 is reactive to ELF4 in Human
Applications
A03714 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
70.73kDa
Background of Elf4/MEF
Transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. Transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. Acts synergistically with RUNX1 to transactivate the IL3 promoter By similarity. Also transactivates the PRF1 promoter in natural killer (NK) cells. Plays a role in the development and function of NK and NK T-cells and in innate immunity. Controls the proliferation and homing of CD8+ T-cells via the Kruppel-like factors KLF4 and KLF2 By similarity. Controls cell senescence in a p53-dependent manner. Can also promote cellular transformation through inhibition of the p16 pathway. UniProtKB Q9Z2U4
Miyazaki Y., Oncogene 13:1721-1729(1996).
Aryee D.N.T., Gene 210:71-78(1998).
Ross M.T., Nature 434:325-337(2005).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blotting: 1:500~1:3000
Validation Images & Assay Conditions
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Western blot analysis of extracts from Jurkat cells, using ELF4 antibody A03714.
Protein Target Info & Infographic
Gene/Protein Information For ELF4 (Source: Uniprot.org, NCBI)
Gene Name
ELF4
Full Name
ETS-related transcription factor Elf-4
Weight
70.73kDa
Superfamily
ETS family
Alternative Names
E74-like factor 4 (ets domain transcription factor); E74-like factor 4; ETS-related transcription factor Elf-4; MEFELFRMyeloid Elf-1-like factor ELF4 ELFR, MEF E74 like ETS transcription factor 4 ETS-related transcription factor Elf-4|E74-like factor 4 (ets domain transcription factor)|myeloid Elf-1-like factor
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ELF4, check out the ELF4 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ELF4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ELF4/Mef Antibody (A03714)
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No publications found for A03714
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