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Product Info Summary
| SKU: | A01302 |
|---|---|
| Size: | 100 µl |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | IHC |
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Product info
Product Name
Anti-Endostatin COL18A1 Antibody
View all Endostatin Antibodies
SKU/Catalog Number
A01302
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-Endostatin COL18A1 Antibody (Catalog # A01302). Tested in IHC applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Endostatin COL18A1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01302)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human endostatin.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01302 is reactive to Col18a1 in Human
Applications
A01302 is guaranteed for IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
182.172kDa
Background of Endostatin
COLA18A probably plays a major role in determining the retinal structure as well as in the closure of the neural tube.Endostatin potently inhibits endothelial cell proliferation and angiogenesis. May inhibit angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling.
Takayuki Furumatsu, J. Biochem. (Tokyo), Apr 2002; 131: 619 - 626.
Sonja Stahl, Genes Cells, Sep 2005; 10: 929 - 939.
NICOLAI MIOSGE, FASEB J, Oct 1999; 13: 1743.
Nicholas J. MacDonald, J. Biol. Chem., Jun 2001; 276: 25190 - 25196.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Innovating Scientists Reward
If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Immunohistochemistry: 1:50~1:100
Validation Images & Assay Conditions
Click image to see more details
Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue, using Endostatin antibody A01302.
Protein Target Info & Infographic
Gene/Protein Information For Col18a1 (Source: Uniprot.org, NCBI)
Gene Name
Col18a1
Full Name
Collagen alpha-1(XVIII) chain
Weight
182.172kDa
Superfamily
multiplexin collagen family
Alternative Names
antiangiogenic agent; COL18A1; collagen alpha-1(XVIII) chain; collagen, type XVIII, alpha 1; Endostatin; FLJ27325; FLJ34914; human type XVIII collagen10endostatin; KNO; KNO1MGC74745; Knobloch syndrome, type 1; KS; multi-functional protein MFP Col18a1|endo|collagen, type XVIII, alpha 1|collagen alpha-1(XVIII) chain|alpha-1(XVIII) collagen|endostatin|procollagen, type XVIII, alpha 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Col18a1, check out the Col18a1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Col18a1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Endostatin COL18A1 Antibody (A01302)
Hello CJ!
A01302 has been cited in 2 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Zhou J,Li Y,Shi X,Hao S,Zhang F,Guo Z,Gao Y,Guo H,Liu L.Oridonin inhibits tumor angiogenesis and induces vessel normalization in experimental colon cancer.J Cancer 2021;12(11):3257-3264.doi:10.7150/jca.55929.Available from https://www.jcancer.org/v12p3257.htm
Species: Human,Mouse
A01302 usage in article: APP:WB, SAMPLE:COLON TUMOR TISSUE, DILUTION:1:1000
Preliminary investigation of the role of BTB domain-containing 3 gene in the proliferation and metastasis of hepatocellular carcinoma
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Customer Reviews
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Customer Q&As
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Find answers in Q&As, reviews.
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7 Customer Q&As for Anti-Endostatin COL18A1 Antibody
Question
See below the WB image, lot number and protocol we used for kidney pns using anti-Endostatin antibody A01302. Please let me know if you require anything else.
Verified Customer
Verified customer
Asked: 2020-03-11
Answer
Thank you very much for the data. Our lab team are working to resolve this as quickly as possible, and we appreciate your patience and understanding! You have provided everything we needed. Please let me know if there is anything you need in the meantime.
Boster Scientific Support
Answered: 2020-03-11
Question
We want to test anti-Endostatin antibody A01302 on human kidney pns for research purposes, then I may be interested in using anti-Endostatin antibody A01302 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?
Verified Customer
Verified customer
Asked: 2019-12-06
Answer
The products we sell, including anti-Endostatin antibody A01302, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.
Boster Scientific Support
Answered: 2019-12-06
Question
Do you have a BSA free version of anti-Endostatin antibody A01302 available?
Verified Customer
Verified customer
Asked: 2019-11-11
Answer
We appreciate your recent telephone inquiry. I can confirm that some lots of this anti-Endostatin antibody A01302 are BSA free. For now, these lots are available and we can make a BSA free formula for you free of charge. It will take 3 extra days to prepare. If you require this antibody BSA free again in future, please do not hesitate to contact me and I will be pleased to check which lots we have in stock that are BSA free.
Boster Scientific Support
Answered: 2019-11-11
Question
Is a blocking peptide available for product anti-Endostatin antibody (A01302)?
B. Krishna
Verified customer
Asked: 2019-05-24
Answer
We do provide the blocking peptide for product anti-Endostatin antibody (A01302). If you would like to place an order for it please contact [email protected] and make a special request.
Boster Scientific Support
Answered: 2019-05-24
Question
Is this A01302 anti-Endostatin antibody reactive to the isotypes of COL18A1?
Verified Customer
Verified customer
Asked: 2019-05-24
Answer
The immunogen of A01302 anti-Endostatin antibody is Synthesized peptide derived from human endostatin. Could you tell me which isotype you are interested in so I can help see if the immunogen is part of this isotype?
Boster Scientific Support
Answered: 2019-05-24
Question
I was wanting to use your anti-Endostatin antibody for IHC for human kidney pns on frozen tissues, but I want to know if it has been validated for this particular application. Has this antibody been validated and is this antibody a good choice for human kidney pns identification?
Verified Customer
Verified customer
Asked: 2017-05-23
Answer
You can see on the product datasheet, A01302 anti-Endostatin antibody has been tested for IHC on human tissues. We have an innovator award program that if you test this antibody and show it works in human kidney pns in IHC-frozen, you can get your next antibody for free.
Boster Scientific Support
Answered: 2017-05-23
Question
I see that the anti-Endostatin antibody A01302 works with IHC, what is the protocol used to produce the result images on the product page?
G. Rodriguez
Verified customer
Asked: 2016-10-05
Answer
You can find protocols for IHC on the "support/technical resources" section of our navigation menu. If you have any further questions, please send an email to [email protected]
Boster Scientific Support
Answered: 2016-10-05
