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Product Info Summary
| SKU: | A05377 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-FRL1 FMNL1 Antibody
SKU/Catalog Number
A05377
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-FRL1 FMNL1 Antibody (Catalog # A05377). Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
FRL1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-FRL1 FMNL1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05377)
Host
Rabbit
Contents
FRL1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
Rabbit polyclonal FRL1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human FRL1. The immunogen is located within the last 50 amino acids of FRL1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
FRL1 antibody is human, mouse and rat reactive. Three alternatively spliced transcript variants have been observed
Reactive Species
A05377 is reactive to FMNL1 in Human, Mouse, Rat
Applications
A05377 is guaranteed for ELISA, IF, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
121.854kDa
Background of FMNL1
The Formin-like protein 1 (FRL1) gene encodes a formin-related protein which has been implicated in morphogenesis, cyokinesis, and cell polarity. Formins are a conserved class of proteins expressed in all eukaryotes and have one DAD (diaphanous autoregulatory domain), one FH2 (formin homology 2) domain and one GBD/FH3 (Rho GTPase-binding / formin homology 3) domain. FRL1 is located in the cytoplasm and is highly expressed in the spleen, lymph node and bone marrow cells. FRL1 possibly has a role in the control of cell motility, survival of macrophages and cytoskeletal organization.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
FRL1 antibody can be used for detection of FRL1 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of FRL1 in EL4 cell lysate with FRL1 antibody at 1 μg/mL.
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Immunofluorescence of FRL1 in EL4 cells with FRL1 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For FMNL1 (Source: Uniprot.org, NCBI)
Gene Name
FMNL1
Full Name
Formin-like protein 1
Weight
121.854kDa
Superfamily
formin homology family
Alternative Names
C17orf1BMGC133052; C17orf1KW-13; CLL-associated antigen KW-13; FHOD4; FMNLMGC1894; formin-like 1; formin-like protein 1; formin-like; Leukocyte formin; MGC21878 FMNL1 C17orf1, C17orf1B, FHOD4, FMNL, KW-13 formin like 1 formin-like protein 1|CLL-associated antigen KW-13|leukocyte formin
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on FMNL1, check out the FMNL1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for FMNL1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-FRL1 FMNL1 Antibody (A05377)
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No publications found for A05377
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Customer Reviews
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