Product Info Summary
SKU: | A02545 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IHC |
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Product info
Product Name
Anti-GABAA R Alpha 1 (L361) GABRA1 Antibody
View all GABA-AR alpha 1 Antibodies
SKU/Catalog Number
A02545
Size
100ul
Form
Liquid
Description
Boster Bio Anti-GABAA R Alpha 1 (L361) GABRA1 Antibody catalog # A02545. Tested in IHC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-GABAA R Alpha 1 (L361) GABRA1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02545)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human PEG3.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02545 is reactive to GABRA1 in Human, Mouse, Rat
Applications
A02545 is guaranteed for IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
51.802kDa
Background of GABA-AR alpha 1
Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B By similarity. Possesses a tumor suppressing activity in glioma cells.
Van den Veyver I.B., J. Soc. Gynecol. Invest. 8:305-313(2001).
Kohda T., Genes Cells 6:237-247(2001).
Hiby S.E., Hum. Mol. Genet. 10:1093-1100(2001).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC: 1:50-1:200
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For GABRA1 (Source: Uniprot.org, NCBI)
Gene Name
GABRA1
Full Name
Gamma-aminobutyric acid receptor subunit alpha-1
Weight
51.802kDa
Superfamily
ligand-gated ion channel (TC 1.A.9) family
Alternative Names
ECA4; EJM; EJM5GABA(A) receptor subunit alpha-1; GABA A R alpha 1; GABAAR alpha 1; GABAARa1; GABRA1; gamma-aminobutyric acid (GABA) A receptor, alpha 1; gamma-aminobutyric acid receptor subunit alpha-1 GABRA1 DEE19, ECA4, EIEE19, EJM, EJM5 gamma-aminobutyric acid type A receptor subunit alpha1 gamma-aminobutyric acid receptor subunit alpha-1|GABA(A) receptor subunit alpha-1|GABA(A) receptor, alpha 1|gamma-aminobutyric acid (GABA) A receptor, alpha 1|gamma-aminobutyric acid type A receptor alpha1 subunit
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on GABRA1, check out the GABRA1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for GABRA1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-GABAA R Alpha 1 (L361) GABRA1 Antibody (A02545)
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No publications found for A02545
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