This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
GABRA1 Antibodies
AND GABRA1 ELISA kits, GABRA1 Proteins
Many biological assays use antibodies to detect GABRA1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GABRA1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GABRA1 antibodies...
Designing a Western blot for GABRA1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the GABRA1 Western Blot GuideDesigning an IHC experiment for GABRA1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the GABRA1 IHC GuideGABRA1 Infographic by Boster Bio
All GABRA1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IHC, WB
$370
Cat # PA1578
100 μg/vial
Cat # PA1578
100 μg/vial
Human
$628
Cat # LS002554
20 µg, 100 µg
Cat # LS002554
20 µg, 100 µg
GABRA1 Overview
Facts about Gamma-aminobutyric acid receptor subunit alpha-1.
Gamma-aminobutyric acid receptor subunit alpha-1 (GABRA1)
Part of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine.
Functions as receptor for diazepines and various anesthetics, such as pentobarbital; those are bound at a different allosteric effector binding site. Functions as ligand- gated chloride channel (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | GABRA1 |
| Uniprot: | P14867 |
| Entrez: | 2554 |
Family
| Belongs to: |
|---|
| ligand-gated ion channel (TC 1.A.9) family |
Alternative Names
ECA4; EJM; EJM5GABA(A) receptor subunit alpha-1; GABA A R alpha 1; GABAAR alpha 1; GABAARa1; GABRA1; gamma-aminobutyric acid (GABA) A receptor, alpha 1; gamma-aminobutyric acid receptor subunit alpha-1
Molecular Weight
Mass (kDA):
51.802 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q34 |
| Sequence: | 5; NC_000005.10 (161847191..161899971) |
Subcellular Localizations
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane.
Diseases
- Epilepsy
- Epilepsy, Generalized
- Epilepsies, Myoclonic
- Myoclonic Epilepsy, Juvenile
- Nervousness
- Absence Epilepsy
- Schizophrenia
- Febrile Convulsions
- Anxiety Disorders
- Depressive Disorder
- Nervous System Disorder
- Bipolar Disorder
Pathways
- Pathogenesis
- Synaptic Transmission
- Localization
- Reflex
- Righting Reflex
- Translation
- Methylation
- Cell Death
- Synapse Maturation
- Brain Development
- Cell Proliferation
- Signal Transmission
- Response To Hypoxia
PTMs
- Phosphorylation
Research Areas
- Neuronal Cell Markers
- Neuroscience
- Neurotransmission
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GABRA1
bosterbio.com/bosterbio-gene-info-cards/GABRA1
References
PMID: 2465923 by Schofield P.R., et al. Sequence and expression of human GABAA receptor alpha 1 and beta 1 subunits.
PMID: 2847710 by Garrett K.M., et al. Isolation of a cDNA clone for the alpha subunit of the human GABA-A receptor.
1 Publications of Boster GABRA1 Antibodies & ELISA Kits
- PubMed ID: 27895756, Role of microRNA-4458 in patients with non-small-cell lung cancer
*More publications can be found for each product on its corresponding product page