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Product Info Summary
| SKU: | A02677 |
|---|---|
| Size: | 100 µl |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IF |
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Product info
Product Name
Anti-GluR1 (Ab-863) Antibody
SKU/Catalog Number
A02677
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-GluR1 (Ab-863) Antibody (Catalog # A02677). Tested in IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-GluR1 (Ab-863) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02677)
Host
Rabbit
Contents
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Clone Number
5H2
Isotype
IgG
Immunogen
Peptide sequence around aa.861~865 (R-N-S-G-A) derived from Human GluR1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02677 is reactive to GRIA1 in Human, Mouse, Rat
Applications
A02677 is guaranteed for IF Boster Guarantee
Observed Molecular Weight
39 kDa
Calculated molecular weight
101.506kDa
Background of GluR1
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of a-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Emamian ES, et al. (2004) J Neurosci. 24(7): 1561-4
Palmer, C.L. et al. (2005) Pharmacol. Rev. 57, 253-277.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Predicted MW: 110kd
Immunofluorescence: 1:100~1:200
Validation Images & Assay Conditions
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Immunofluorescence staining of methanol-fixed Hela cells using GluR1(Ab-863) Antibody #A02677.
Protein Target Info & Infographic
Gene/Protein Information For GRIA1 (Source: Uniprot.org, NCBI)
Gene Name
GRIA1
Full Name
Glutamate receptor 1
Weight
101.506kDa
Superfamily
glutamate-gated ion channel (TC 1.A.10.1) family
Alternative Names
AMPA 1; AMPA-selective glutamate receptor 1; GluA1; GLUH1; GluR1; gluR-1; GLUR1gluR-A; GLURA; GluR-A; gluR-K1; glutamate receptor 1; Glutamate receptor ionotropic, AMPA 1; glutamate receptor, ionotropic, AMPA 1; GRIA1; HBGR1; MGC133252 GRIA1 GLUH1, GLUR1, GLURA, GluA1, HBGR1 glutamate ionotropic receptor AMPA type subunit 1 glutamate receptor 1|AMPA 1|AMPA-selective glutamate receptor 1|gluR-1|gluR-A|gluR-K1|glutamate receptor, ionotropic, AMPA 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on GRIA1, check out the GRIA1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for GRIA1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-GluR1 (Ab-863) Antibody (A02677)
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No publications found for A02677
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Customer Reviews
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