Anti-GNL3 Antibody

Nucleostemin antibody

Boster Bio Anti-GNL3 Antibody catalog # A03283-2. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A03283-2
Size: 100ul
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, WB

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Product Name

Anti-GNL3 Antibody

View all Nucleostemin Antibodies

SKU/Catalog Number

A03283-2

Size

100ul

Form

Liquid

Description

Boster Bio Anti-GNL3 Antibody catalog # A03283-2. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-GNL3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03283-2)

Host

Rabbit

Contents

Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human Girdin around the phosphorylation site of S1417.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A03283-2 is reactive to GNL3 in Human, Mouse, Rat

Applications

A03283-2 is guaranteed for ELISA, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

61.993kDa

Background of Nucleostemin

Plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Enhances phosphoinositide 3-kinase (PI3K)-dependent phosphorylation and kinase activity of AKT1/PKB, but does not possess kinase activity itself. Phosphorylation of AKT1/PKB thereby induces the phosphorylation of downstream effectors GSK3 and FOXO1/FKHR, and regulates DNA replication and cell proliferation By similarity. Essential for the integrity of the actin cytoskeleton and for cell migration. Required for formation of actin stress fibers and lamellipodia. May be involved in membrane sorting in the early endosome.

Enomoto A., Dev. Cell 9:389-402(2005).
Simpson F., Traffic 6:442-458(2005).
Hillier L.W., Nature 434:724-731(2005).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-2000 ELISA 1:5000-20000

Validation Images & Assay Conditions

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Gene/Protein Information For GNL3 (Source: Uniprot.org, NCBI)

Gene Name

GNL3

Full Name

Guanine nucleotide-binding protein-like 3

Weight

61.993kDa

Superfamily

TRAFAC class YlqF/YawG GTPase family

Alternative Names

C77032; E2IG3NNP47; estradiol-induced nucleotide binding protein; GNL3; guanine nucleotide binding protein-like 3 (nucleolar); guanine nucleotide-binding protein-like 3; MGC800; Novel nucleolar protein 47; NSE2-induced gene 3 protein; Nucleolar GTP-binding protein 3; Nucleostemin GNL3 C77032, E2IG3, NNP47, NS G protein nucleolar 3 guanine nucleotide-binding protein-like 3|E2-induced gene 3 protein|estradiol-induced nucleotide binding protein|guanine nucleotide binding protein-like 3 (nucleolar)|novel nucleolar protein 47|nucleolar GTP-binding protein 3|nucleostemin

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on GNL3, check out the GNL3 Infographic

GNL3 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for GNL3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A03283-2-100ul

100ul

$380

Free Secondary Antibody

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