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Product Info Summary
| SKU: | A03374-1 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-Grik2 Antibody
View all Glutamate Receptor 6 Antibodies
SKU/Catalog Number
A03374-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Grik2 Antibody (Catalog # A03374-1). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Grik2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Grik2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03374-1)
Host
Rabbit
Contents
Grik2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Grik2 antibody was raised against a 13 amino acid synthetic peptide near the carboxy terminus of the human Grik2. The immunogen is located within the last 50 amino acids of Grik2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least three isoforms of TET3 are known to exist. TET3 antibody is predicted to not cross react with other TET proteins.
Reactive Species
A03374-1 is reactive to GRIK2 in Human, Mouse, Rat
Applications
A03374-1 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
102.583kDa
Background of Glutamate Receptor 6
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik2, also known as glutamate receptor 6, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Recent reports have suggested that defects in the Grik2 protein may be associated with autosomal recessive mental retardation and possibly other neurological disorders such as schizophrenia. Numerous isoforms of Grik2 are known to exist and may be subject to RNA editing within the second transmembrane domain, which is thought to alter the properties of ion flow. This Grik2 antibody may exhibit some cross-reactivity to Grik3.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Grik2 antibody can be used for detection of Grik2 by Western blot at 0.5 - 1 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of Grik2 in human brain tissue lysate with Grik2 antibody at (A) 0.5 and (B) 1 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For GRIK2 (Source: Uniprot.org, NCBI)
Gene Name
GRIK2
Full Name
Glutamate receptor ionotropic, kainate 2
Weight
102.583kDa
Superfamily
glutamate-gated ion channel (TC 1.A.10.1) family
Alternative Names
EAA4; glutamate receptor 6; glutamate receptor, ionotropic, kainate 2; ionotropic kainate 2; MGC74427 GRIK2 EAA4, GLR6, GLUK6, GLUR6, GluK2, MRT6 glutamate ionotropic receptor kainate type subunit 2 glutamate receptor ionotropic, kainate 2|bA487F5.1|excitatory amino acid receptor 4|gluR-6|glutamate receptor 6|glutamate receptor form A|glutamate receptor form B|glutamate receptor form C|glutamate receptor form D|glutamate receptor form E
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on GRIK2, check out the GRIK2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for GRIK2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Grik2 Antibody (A03374-1)
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No publications found for A03374-1
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