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Product Info Summary
| SKU: | M00851-2 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | ELISA, IHC-P, ICC |
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Product info
Product Name
Anti-hGH Purified GH1 Monoclonal Antibody
View all Growth Hormone Antibodies
SKU/Catalog Number
M00851-2
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-hGH Purified GH1 Monoclonal Antibody (Catalog# M00851-2). Tested in IHC-P, ICC, ELISA application(s). This antibody reacts with Human.
Storage & Handling
Store at 2-8°C. Do not freeze.
Cite This Product
Anti-hGH Purified GH1 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00851-2)
Host
Mouse
Contents
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Clonality
Monoclonal
Clone Number
GH-45
Isotype
Mouse IgG1
Immunogen
Human growth hormone. The mouse monoclonal antibody GH-45 recognizes human growth hormone (hGH), a polypeptide hormone synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. The GH-45 antibody reacts with affinity constant 3.8 x 1010 l /mol; it does not bind human prolactin or any other pituitary hormones.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M00851-2 is reactive to GH1 in Human
Applications
M00851-2 is guaranteed for ELISA, IHC-P, ICC Boster Guarantee
Observed Molecular Weight
42 kDa
Calculated molecular weight
24.847kDa
Background of Growth Hormone
CD107a (lysosome-associated membrane protein-1, LAMP-1), together with LAMP-2, is a major constituent of lysosomal membrane, 1-2% of total CD107a is found also on the plasma membrane. The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes. Increased CD107a immunoreactivity is observed in neurones, and in glial cells surrounding senile plaques in Alzheimers disease cases and is localized mainly in medullary epithelial cells, single macrophages and lymphocytes in acute thymic involution. CD107a is a good marker of mast cell activation.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Immunohistochemistry: 5-10 μg/ml.
Validation Images & Assay Conditions
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Figure 1. ELISA validation of GH1 using Anti-hGH Purified GH1 Monoclonal Antibody (M00851-2).
ELISA of human growth hormone using mouse monoclonal antibody GH-45. Compared with mouse IgG1 isotype control antibody MOPC-21.Protein Target Info & Infographic
Gene/Protein Information For GH1 (Source: Uniprot.org, NCBI)
Gene Name
GH1
Full Name
Somatotropin
Weight
24.847kDa
Superfamily
somatotropin/prolactin family
Alternative Names
GH1; GHB5; GHIGHD1B; GHN; GH-N; GHNGrowth hormone; GH-Nsomatotropin; growth hormone 1Pituitary growth hormone; Growth Hormone; hGH-N; IGHD1A; IGHD2; Somatotropin GH1 GH, GH-N, GHB5, GHN, IGHD1A, IGHD1B, IGHD2, hGH-N growth hormone 1 somatotropin|growth hormone B5|pituitary growth hormone
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on GH1, check out the GH1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for GH1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-hGH Purified GH1 Monoclonal Antibody (M00851-2)
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No publications found for M00851-2
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Customer Reviews
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