Anti-HtrA2/Omi Antibody

HTRA2/Omi antibody

Boster Bio Anti-HtrA2/Omi Antibody (Catalog# A01941-1). Tested in IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A01941-1
Size: 100ul
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, IHC-P, IF (paraffin)

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Product Name

Anti-HtrA2/Omi Antibody

View all HTRA2/Omi Antibodies

SKU/Catalog Number

A01941-1

Size

100ul

Form

Liquid

Description

Boster Bio Anti-HtrA2/Omi Antibody (Catalog# A01941-1). Tested in IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-HtrA2/Omi Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01941-1)

Host

Rabbit

Contents

PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

7A7

Isotype

Rabbit IgG

Immunogen

A peptide derived from human HtrA2. Immunogen sequence location: 181-230

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A01941-1 is reactive to HTRA2 in Human, Mouse, Rat

Applications

A01941-1 is guaranteed for ELISA, IHC-P, IF (paraffin) Boster Guarantee

Observed Molecular Weight

72 kDa

Calculated molecular weight

48.841kDa

Background of HTRA2/Omi

Integrin alpha 1 (ITGA1) chain associates with the beta 1 (ITGB1) chain to form a heterodimer that functions as a dual laminin/collagen receptor in neural cells and hematopoietic cells. ITGA1 has a 206-amino acid I domain in its N-terminal half, followed by 3 divalent cation-binding sites and a C-terminal transmembrane domain with a short cytoplasmic tail. It also has 28 potential N-glycosylation sites. Human ITGA1 was expressed in a mouse fibroblast cell line as a 180-kD protein. ITGA1 is involved in the early remodeling of osteoarthritic cartilage and plays an essential role in the regulation of mesenchymal stem cell proliferation and cartilage production. It also plays an essential role in the regulation of MSC proliferation and cartilage production.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry, 1:100 - 1:300
ELISA, 1:40000
Not yet tested in other applications.

Validation Images & Assay Conditions

Gene/Protein Information For HTRA2 (Source: Uniprot.org, NCBI)

Gene Name

HTRA2

Full Name

Serine protease HTRA2, mitochondrial

Weight

48.841kDa

Superfamily

peptidase S1C family

Alternative Names

High temperature requirement protein A2; HtrA serine peptidase 2; HTRA2; HtrA-like serine protease; Omi; OMIOmi stress-regulated endoprotease; PARK13EC 3.4.21.108; PRSS25; PRSS25serine, 25; Serine protease 25; serine protease HTRA2, mitochondrial; Serine proteinase OMI HTRA2 MGCA8, OMI, PARK13, PRSS25 HtrA serine peptidase 2 serine protease HTRA2, mitochondrial|HtrA-like serine protease|Omi stress-regulated endoprotease|epididymis secretory sperm binding protein|high temperature requirement protein A2|protease, serine, 25|serine protease 25|serine proteinase OMI

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on HTRA2, check out the HTRA2 Infographic

HTRA2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for HTRA2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A01941-1

100 μL

$335

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A01941-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
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