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Product Info Summary
| SKU: | A01965 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC, WB |
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Product info
Product Name
Anti-ICOS ligand ICOSLG Antibody
View all B7-H2/ICOSLG Antibodies
SKU/Catalog Number
A01965
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-ICOS ligand ICOSLG Antibody (Catalog # A01965). Tested in ELISA, WB, IHC, IF applications. This antibody reacts with Human.
Storage & Handling
ICOSLG antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-ICOS ligand ICOSLG Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01965)
Host
Rabbit
Contents
ICOSLG Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
ICOSLG antibody was raised against a peptide corresponding to 17 amino acids near the center of human ICOSLG. The immunogen is located within amino acids 150 - 200 of ICOSLG.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
SRPK1 antibody is human, mouse and rat reactive. Multiple isoforms of SRPK1 are known to exist; this antibody will detect all except isoforms b and e. SRPK1 antibody is predicted to not cross-react with SRPK2.
Reactive Species
A01965 is reactive to ICOSLG in Human
Applications
A01965 is guaranteed for ELISA, IF, IHC, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
33.349kDa
Background of B7-H2/ICOSLG
Inhibitor of apoptosis proteins (IAPs) were initially identified in baculoviruses as proteins that inhibit apoptosis of the host cells to allow time for viral replication. Cellular homologues containing at least one baculoviral IAP repeat (BIR) motif essential for their anti-apoptosis activity have been identified in yeasts and higher organisms and often act by binding and inhibiting processed caspases. The activity of these proteins can be modulated by the expression of proteins such as Smac/DIABLO and XAF-1 which displace or prevent the binding of caspases by IAPs. Recently, a mitochondrial serine protease termed Omi/HtrA2 has been found to bind IAPs. Similar to Smac, Omi possesses a conserved IAP-binding motif, but acts to cleave IAPs to irreversibly inactivate IAPs and promote apoptosis.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ICOSLG antibody can be used for Western blot at 1 μg/mL. Antibody can also be used for Immunohistochemistry at 2 μg/mL. For Immunoflorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of ICOSLG in human lymph node tissue lysate with ICOSLG antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunohistochemistry of ICOSLG in human lymph node tissue with ICOSLG antibody at 2 μg/ml.
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Immunofluorescence of ICOSLG in human lymph node tissue with ICOSLG antibody at 20 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For ICOSLG (Source: Uniprot.org, NCBI)
Gene Name
ICOSLG
Full Name
ICOS ligand
Weight
33.349kDa
Superfamily
immunoglobulin superfamily
Alternative Names
B7H2; B7-H2; B7H2B7 homolog 2; B7-H2B7-related protein 1; B7RP-1; B7RP1B7-like protein Gl50; B7RP-1LICOS; CD275 antigen; CD275; GL50; GL50transmembrane protein B7-H2 ICOS ligand; ICOSL; ICOS-L; ICOSLG; inducible T-cell co-stimulator ligand; KIAA0653ICOS ligand ICOSLG B7-H2, B7H2, B7RP-1, B7RP1, B7h, CD275, GL50, ICOS-L, ICOSL, LICOS inducible T cell costimulator ligand ICOS ligand|B7 homolog 2|B7 homologue 2|B7-like protein Gl50|B7-related protein 1|transmembrane protein B7-H2 ICOS ligand
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ICOSLG, check out the ICOSLG Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ICOSLG: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ICOS ligand ICOSLG Antibody (A01965)
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No publications found for A01965
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