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- Table of Contents
ECM1 Antibodies
AND ECM1 ELISA kits, ECM1 Proteins
Many biological assays use antibodies to detect ECM1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ECM1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ECM1 antibodies...
Designing an IHC experiment for ECM1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the ECM1 IHC GuideECM1 Infographic by Boster Bio
All ECM1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M02861-1
100 μl/vial
Cat # M02861-1
100 μl/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A02861-2
100 μg/vial
Cat # A02861-2
100 μg/vial
ECM1 Overview
Facts about Extracellular matrix protein 1.
Extracellular matrix protein 1 (ECM1)
Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis.
Inhibits MMP9 proteolytic activity. .
Gene Information
| Human | |
|---|---|
| Gene Name: | ECM1 |
| Uniprot: | Q16610 |
| Entrez: | 1893 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
ECM1; extracellular matrix protein 1; p85; Secretory Component Glycoprotein; Secretory Component P85
Molecular Weight
Mass (kDA):
60.674 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q21.2 |
| Sequence: | 1; NC_000001.11 (150508109..150513789) |
Tissue Specificity
Expressed in breast cancer tissues. Little or no expression observed in normal breast tissues. Expressed in skin; wide expression is observed throughout the dermis with minimal expression in the epidermis.
Subcellular Localizations
Secreted, extracellular space, extracellular matrix.
Diseases
- Lipoid Proteinosis Of Urbach And Wiethe
- Neoplasms
- Cicatrix
- Hoarseness
- Malignant Neoplasms
- Neoplasm Metastasis
- Carcinoma
- Tumor Angiogenesis
- Skin Diseases, Genetic
- Tissue Adhesions
- Lichen Sclerosus Et Atrophicus
- Lichen Disease
Pathways
- Angiogenesis
- Pathogenesis
- Localization
- Cell Adhesion
- Cell Migration
- Cell Proliferation
- Wound Healing
- Methylation
- Autophagy
- Secretion
- Cell Differentiation
- Humoral Immune Response
- Immune Response
PTMs
- Phosphorylation
Research Areas
- Extracellular Matrix
- Immunology
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ECM1
bosterbio.com/bosterbio-gene-info-cards/ECM1
References
PMID: 9367673 by Smits P., et al. The human extracellular matrix gene 1 (ECM1): genomic structure, cDNA cloning, expression pattern, and chromosomal localization.
PMID: 9501329 by Johnson M.R., et al. Characterization of the human extracellular matrix protein 1 gene on chromosome 1q21.