Anti-Mannose 6 Phosphate Receptor/Igf2r Antibody Picoband™

IGF-II R/IGF2R antibody

Boster Bio Anti-Mannose 6 Phosphate Receptor/Igf2r Antibody Picoband™ catalog # A00951-1. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat. Cited in 1 publication(s).

Product Info Summary

SKU: A00951-1
Size: 100 μg/vial
Reactive Species: Mouse, Rat
Host: Rabbit
Application: IHC, WB

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Product Name

Anti-Mannose 6 Phosphate Receptor/Igf2r Antibody Picoband™

View all IGF-II R/IGF2R Antibodies

SKU/Catalog Number

A00951-1

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Mannose 6 Phosphate Receptor/Igf2r Antibody Picoband™ catalog # A00951-1. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Mannose 6 Phosphate Receptor/Igf2r Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00951-1)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of mouse Igf2r, which shares 70.6% and 94.1% amino acid (aa) sequence identity with human and rat Igf2r, respectively.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A00951-1 is reactive to IGF2R in Mouse, Rat

Applications

A00951-1 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

274 kDa

Calculated molecular weight

274.375kDa

Background of IGF-II R/IGF2R

Insulin-like growth factor 2 receptor, also called IGF2R or I-MPR is a protein that in humans is encoded by the IGF2R gene. This gene is mapped to 6q25.3. This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml

Validation Images & Assay Conditions

Gene/Protein Information For IGF2R (Source: Uniprot.org, NCBI)

Gene Name

IGF2R

Full Name

Cation-independent mannose-6-phosphate receptor

Weight

274.375kDa

Superfamily

MRL1/IGF2R family

Alternative Names

300 kDa mannose 6-phosphate receptor; cation-independent mannose-6 phosphate receptor; cation-independent mannose-6-phosphate receptor; CD222 antigen; CD222; CI Man-6-P receptor; CIMPR; CI-MPR; IGF2R; IGF-II R; IGF-II receptor; IGFIIR; IGF-IIR; insulin-like growth factor 2 receptorM6P/IGF2R; Insulin-like growth factor II receptor; M6P/IGF2 receptor; M6PR; M6P-R; MPR 300; MPR1; MPRI; MPRIM6PR IGF2R CD222, CI-M6PR, CIMPR, M6P-R, M6P/IGF2R, MPR 300, MPR1, MPR300, MPRI insulin like growth factor 2 receptor cation-independent mannose-6-phosphate receptor|300 kDa mannose 6-phosphate receptor|CI Man-6-P receptor|IGF-II receptor|M6P/IGF2 receptor|insulin-like growth factor II receptor

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on IGF2R, check out the IGF2R Infographic

IGF2R infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for IGF2R: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

A00951-1 has been cited in 1 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Insulin-like growth factors in endometrioid adenocarcinoma: Correlation with clinico-pathological features and estrogen receptor expression

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Order DetailsPrice
A00951-1

100μg

$370
A00951-1-10ug

10μg sample (liquid)

$99
A00951-1-Biotin

100 μg Biotin conjugated

$570
A00951-1-Cy3

100 μg Cy3 conjugated

$570
A00951-1-Dylight488

100 μg Dylight488 conjugated

$570
A00951-1-Dylight550

100 μg Dylight550 conjugated

$570
A00951-1-Dylight594

100 μg Dylight594 conjugated

$570
A00951-1-FITC

100 μg FITC conjugated

$570
A00951-1-HRP

100 μg HRP conjugated

$570
A00951-1-APC

100 μg APC conjugated

$670
A00951-1-PE

100 μg PE conjugated

$670
A00951-1-carrier-free

Carrier Free

$370

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Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
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