Anti-IL-17RE Antibody (Monoclonal, ABM2G70)

Product Name

Anti-IL-17RE Antibody (Monoclonal, ABM2G70)

View all IL-17RE Antibodies

SKU/Catalog Number

M11492

Size

100 µg

Form

Liquid

Description

Boster Bio Anti-IL-17RE Antibody (Monoclonal, ABM2G70) (Catalog# M11492). Tested in FACS, WB application(s). This antibody reacts with Human, Mouse.

Storage & Handling

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Cite This Product

Anti-IL-17RE Antibody (Monoclonal, ABM2G70) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M11492)

Host

Mouse

Contents

100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide.

Clonality

Monoclonal

Clone Number

ABM2G70

Isotype

IgG2b Kappa

Immunogen

A partial length recombinant human IL-17RE protein (amino acids 50-268)

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

Does not cross-react with primate, avian or amphibian GR.

Reactive Species

M11492 is reactive to Il17re in Human, Mouse

Applications

M11492 is guaranteed for WB, FACS Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

70.833kDa

Background of IL-17RE

The regions of relatively constant sequence beyond the variable regions of immunoglobulins are termed constant regions (C regions) and are present in both the heavy and light chains. With very few exceptions, the sites of attachment for carbohydrates on immunoglobulins are located in these C regions. These regions also function to hold the variable regions together by using the disulfide bond between them. The C regions facilitate interaction with the antigen by increasing the maximum rotation of the immunoglobulin arms. Reportedly, a large population of patients with recurrent respiratory tract infection has low IgG4 concentrations. IgG4-related sclerosing disease has been recognized as a systemic disease entity characterized by an elevated serum IgG4 level, sclerosing fibrosis, and diffuse lymphoplasmacytic infiltration with the presence of many IgG4-positive plasma cells.IgG4 is overexpressed in inflammatory pseudotumor (IPT) and under expressed in inflammatory myofibroblastic tumor (IMT). In pulmonary nodular lymphoid hyperplasia (PNLH), there are an increased number of IgG4+ plasma cells.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Reconstitute with distilled water.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot: 2-4 µg/ml
Flow cytometry: 2-4 µg/10^6 Cells

Validation Images & Assay Conditions

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Western blot analysis of IL-17RE. Anti-IL-17RE antibody (Clone: ABM2G70) was tested at 2 μg/ml on (1) Jurkat, (2) PC3 and (3) NIH3T3 lysates.

Gene/Protein Information For Il17re (Source: Uniprot.org, NCBI)

Alternative Names

IL-17 RE; IL-17 receptor E; IL17RE; IL-17RE; Il25r; interleukin 17 receptor E Il17re|AA589509, IL-17RE, Il, Il25r|interleukin 17 receptor E|interleukin-17 receptor E|IL-17 receptor E

For more info on Il17re, check out the Il17re Infographic

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In this infographic, you will see the following information for Il17re: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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