Anti-IL-1RAcP IL1RAP Antibody

Product Name

Anti-IL-1RAcP IL1RAP Antibody

View all IL1RAP Antibodies

SKU/Catalog Number

A02824

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-IL-1RAcP IL1RAP Antibody (Catalog # A02824). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human.

Storage & Handling

IL-1RAcP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-IL-1RAcP IL1RAP Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02824)

Host

Rabbit

Contents

IL-1RAcP Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

IL-1RAcP antibody was raised against a 16 amino acid peptide near the carboxy terminus of human IL-1RAcP. The immunogen is located within the last 50 amino acids of IL-1RAcP.

Cross-reactivity

This polyclonal antibody has no cross activity to other members in the IL-1 receptor family.

Reactive Species

A02824 is reactive to IL1RAP in Human

Observed Molecular Weight

68 kDa

Calculated molecular weight

65.4 kDa

Background of IL1RAP

The pro-inflammatory cytokine IL-1 induced cellular response requires two subunits of its receptor, IL-1 receptor I (IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP). IL-1RAcP forms a complex with IL-1RI in response to IL-1 treatment. The IL-1 receptor-associated kinase (IRAK), which mediates activation of NF-κB inducing kinae (NIK) and of NF-κB, recruits to the IL-1R complex through IL-1RAcP. IL-1 activation of stress-activated protein kinase and of acid sphingomyelinase also requires IL-1RAcP. Like IL-1RI, IL-1RAcP subunit is essential for IL-1 mediated cellular response. IL-1RAcP is expressed in many tissues.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A02824 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

IL-1RAcP antibody can be used for detection of IL-1RAcP by Western blot at 1 μg/mL. Antibody can also be used for Immunohistochemistry starting at 2 μg/mL. For immunofluorescence start at 5 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information IL1RAP

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