Product Info Summary
SKU: | A05759 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human |
Host: | Rabbit |
Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-IL-36G Antibody
View all IL-36 gamma/IL-1F9 Antibodies
SKU/Catalog Number
A05759
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-IL-36G Antibody (Catalog # A05759). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human.
Storage & Handling
IL-36G antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-IL-36G Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05759)
Host
Rabbit
Contents
IL-36G antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
IL-36G antibody was raised against a 13 amino acid peptide near the carboxy terminus of human IL-36G. The immunogen is located within the last 50 amino acids of IL-36G.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
IL-36G antibody is human specific. IL-36G antibody will not cross-react with IL-36A or IL-36B.
Reactive Species
A05759 is reactive to IL36G in Human
Applications
A05759 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
18.721kDa
Background of IL-36 gamma/IL-1F9
IL-36G is is a member of the interleukin 1 cytokine family whose gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2 (1). IL-36G is thought to activate the NF-kappaB pathway through IL-1 receptor family members IL-1RL2 and IL-1RAcP (2). Like the related proteins IL-36A and IL-36B, IL-36G requires post-translational processing for full agonist activity, but the cleavage mechanism is currently unknown (3). IL-36G expression is stimulated by interferon-gamma, tumor necrosis factor-alpha and interleukin 1 (4). The IL-36 cytokines have been suggested to amplify Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells (5).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IL-36G antibody can be used for detection of IL-36G by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of IL-36G in human spleen tissue lysate with IL-36G antibody at (A) 1 and (B) 2 μg/ml.
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Immunohistochemistry of IL-36G in human bladder tissue with IL-36G antibody at 5 μg/mL.
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Immunofluorescence of IL-36G in human bladder tissue with IL-36G antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For IL36G (Source: Uniprot.org, NCBI)
Gene Name
IL36G
Full Name
Interleukin-36 gamma
Weight
18.721kDa
Superfamily
IL-1 family
Alternative Names
IL-1 epsilon; IL-1 H1; IL-1 Related Protein 2; IL-1(EPSILON); IL1E; IL-1-epsilon; IL1F9; IL-1F9; IL1H1; IL-1H1; IL-1-Related Protein 2; IL1RP2; IL-1rp2; IL36 gamma; IL-36 gamma; IL36G; interleukin 1 family, member 9; interleukin 1-related protein 2; Interleukin 36, Gamma; Interleukin-1 epsilon; interleukin-1 family member 9; Interleukin-1 homolog 1; Interleukin-36 Gamma IL36G IL-1F9, IL-1H1, IL-1RP2, IL1E, IL1F9, IL1H1, IL1RP2 interleukin 36 gamma interleukin-36 gamma|IL-1 related protein 2|IL-1-epsilon|interleukin 1-related protein 2|interleukin-1 epsilon|interleukin-1 family member 9|interleukin-1 homolog 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on IL36G, check out the IL36G Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for IL36G: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-IL-36G Antibody (A05759)
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Customer Reviews
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