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Product Info Summary
| SKU: | A01561-1 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | Flow Cytometry, WB |
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Product info
Product Name
Anti-Integrin Alpha V ITGAV Antibody
SKU/Catalog Number
A01561-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Integrin Alpha V ITGAV Antibody catalog # A01561-1. Tested in WB,Flow Cytometry applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Integrin Alpha V ITGAV Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01561-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Bim around the phosphorylation site of S59.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01561-1 is reactive to ITGAV in Human, Mouse, Rat
Applications
A01561-1 is guaranteed for Flow Cytometry, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
116.038kDa
Background of ITGAV
Induces apoptosis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-a1, isoform Bim-a2 and isoform Bim-a3 induce apoptosis, although less potent than the isoforms BimEL, BimL and BimS. Isoform Bim-gamma induces apoptosis.
Fukazawa H, et al. (2004) Mol Cancer Ther ; 3(10): 1281-1288
Luciano F, et al. (2003) Oncogene ; 22(43): 6785-6793
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:1,000-1:2,000
FC: 1:50-1:100
Validation Images & Assay Conditions
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Figure 2. Flow Cytometry validation of ITGAV using Anti-Integrin Alpha V ITGAV Antibody (A01561-1).
Flow cytometric analysis of MCF-7 cells with Integrin alpha V antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
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Figure 1. Western blotting validation for Anti-Integrin Alpha V ITGAV Antibody A01561-1
Western blot analysis of Integrin alpha V+beta 6 on different lysates using anti-Integrin alpha V+beta 6 antibody at 1/1Protein Target Info & Infographic
Gene/Protein Information For ITGAV (Source: Uniprot.org, NCBI)
Gene Name
ITGAV
Full Name
Integrin alpha-V
Weight
116.038kDa
Superfamily
integrin alpha chain family
Alternative Names
CD51; Integrin alpha V beta 5; integrin subunit alpha V; ITGAV; MSK8; VNRA; VTNR ITGAV CD51, MSK8, VNRA, VTNR integrin subunit alpha V integrin alpha-V|antigen identified by monoclonal antibody L230|integrin alphaVbeta3|integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)|vitronectin receptor subunit alpha
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ITGAV, check out the ITGAV Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ITGAV: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Integrin Alpha V ITGAV Antibody (A01561-1)
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No publications found for A01561-1
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