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- Table of Contents
Integrin alpha-V Antibodies
AND ITGAV ELISA kits, Integrin alpha-V Proteins
Many biological assays use antibodies to detect Integrin alpha-V, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Integrin alpha-V in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Integrin alpha-V antibodies...
Designing a Western blot for Integrin alpha-V? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ITGAV Western Blot GuideITGAV Infographic by Boster Bio
All ITGAV Products
Product
Figures
Specificity
Applications
Price
Human
IF, IHC, ICC, WB
$370
Cat # M01561-2
100 μg/vial
Cat # M01561-2
100 μg/vial
Human, Mouse, Rat
IP, IF, IHC, ICC, WB
$370
Cat # M01561
100 μl
Cat # M01561
100 μl
Anti-Integrin alpha V/ITGAV Antibody Picoband®
3 Citations
Human
ELISA, Flow Cytometry, WB
$370
Cat # A01561-2
100 μg/vial
Cat # A01561-2
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01561-1
100 μl
Cat # M01561-1
100 μl
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01561-6
100 μg
Cat # M01561-6
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01561-5
100 μg
Cat # M01561-5
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01561-4
100 μg
Cat # M01561-4
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01561-3
100 μg
Cat # M01561-3
100 μg
ITGAV Overview
Facts about Integrin alpha-V.
Integrin alpha-V (ITGAV)
The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands.
ITGAV:ITGB3 binds to NRG1 (through EGF domain name ) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGAV:ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling (PubMed:18441324).
Gene Information
| Human | |
|---|---|
| Gene Name: | ITGAV |
| Uniprot: | P06756 |
| Entrez: | 3685 |
Family
| Belongs to: |
|---|
| integrin alpha chain family |
Alternative Names
CD51; Integrin alpha V beta 5; integrin subunit alpha V; ITGAV; MSK8; VNRA; VTNR
Molecular Weight
Mass (kDA):
116.038 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q32.1 |
| Sequence: | 2; NC_000002.12 (186590056..186680902) |
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein. Cell junction, focal adhesion.
Diseases
- Neoplasms
- Tissue Adhesions
- Malignant Neoplasms
- Tumor Angiogenesis
- Cell Invasion
- Carcinoma
- Neoplasm Metastasis
- Rheumatoid Arthritis
- Arthritis
- Metastatic Malignant Neoplasm To The Lymph Node
- Cell Transformation, Neoplastic
- Melanoma
Interacting Proteins
- ITGB3
- ITGB5
- ITGB6
Pathways
- Angiogenesis
- Cell Adhesion
- Cell Proliferation
- Cell Cycle
- Cell-matrix Adhesion
- Integrin Activation
- Pathogenesis
- Osteoblast Differentiation
- Tube Formation
- Immune Response
- Vasculogenesis
- Embryo Development
- Platelet Aggregation
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ITGAV
bosterbio.com/bosterbio-gene-info-cards/ITGAV
References
PMID: 2443500 by Suzuki S., et al. Amino acid sequence of the vitronectin receptor alpha subunit and comparative expression of adhesion receptor mRNAs.
PMID: 10965141 by Sims M.A., et al. Cloning and characterisation of ITGAV, the genomic sequence for human cell adhesion protein (vitronectin) receptor alpha subunit, CD51.
9 Publications of Boster Integrin alpha-V Antibodies & ELISA Kits
- PubMed ID: 10.3390/ijms12063409, Study on the Expression and Clinical Significances of Lewis y Antigen and Integr...
- PubMed ID: 10.1038/srep20587, TGFβ3-mediated induction of Periostin facilitates head and neck cancer growth a...
- PubMed ID: 10.1002/ar.21398, Overexpression of Lewis (y) Antigen Protects Ovarian Cancer RMG‐1 Cells from C...
- PubMed ID: 10.1002/ar.21398, Overexpression of Lewis (y) Antigen Protects Ovarian Cancer RMG‐1 Cells from C...
- PubMed ID: 10.1002/ar.21398, Overexpression of Lewis (y) Antigen Protects Ovarian Cancer RMG‐1 Cells from C...
- PubMed ID: 21747684, Study on the Expression and Clinical Significances of Lewis y Antigen and Integr...
- PubMed ID: 26857387, TGF?3-mediated induction of Periostin facilitates head and neck cancer growth an...
- PubMed ID: 29312560, Xuan J, Chen Y, Zhu L, Guo Y, Deng L, Zheng Y, Wang Z, Wang Z, Ao M. Oncotarget....
- PubMed ID: 25666351, Chen Q, Zhang Z, Liu J, He Q, Zhou Y, Shao G, Sun X, Cao X, Gong A, Jiang P. Mol...
*More publications can be found for each product on its corresponding product page