This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Integrin alpha-V Antibodies
AND ITGAV ELISA kits, Integrin alpha-V Proteins
Many biological assays use antibodies to detect Integrin alpha-V, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Integrin alpha-V in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Integrin alpha-V antibodies...
Previous: CBLIF
Next: ITGB6
ITGAV Infographic by Boster Bio
All ITGAV Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01561-1
100 μl
Cat # M01561-1
100 μl
Anti-Integrin alpha V ITGAV Rabbit Monoclonal Antibody
1 Citations 4 Q&As
Human, Mouse, Rat
IP, IF, IHC, ICC, WB
$370
Cat # M01561
100 μl
Cat # M01561
100 μl
Anti-Integrin alpha V/ITGAV Antibody Picoband®
3 Citations
Human
ELISA, Flow Cytometry, WB
$370
Cat # A01561-2
100 μg/vial
Cat # A01561-2
100 μg/vial
Human
IF, IHC, ICC, WB
$370
Cat # M01561-2
100 μg/vial
Cat # M01561-2
100 μg/vial
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01561-5
100 μg
Cat # M01561-5
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01561-6
100 μg
Cat # M01561-6
100 μg
ITGAV Overview
Facts about Integrin alpha-V.
Integrin alpha-V (ITGAV)
The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands.
ITGAV:ITGB3 binds to NRG1 (through EGF domain name ) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGAV:ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling (PubMed:18441324).
Gene Information
| Human | |
|---|---|
| Gene Name: | ITGAV |
| Uniprot: | P06756 |
| Entrez: | 3685 |
Family
| Belongs to: |
|---|
| integrin alpha chain family |
Alternative Names
CD51; Integrin alpha V beta 5; integrin subunit alpha V; ITGAV; MSK8; VNRA; VTNR
Molecular Weight
Mass (kDA):
116.038 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q32.1 |
| Sequence: | 2; NC_000002.12 (186590056..186680902) |
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein. Cell junction, focal adhesion.
Diseases
- Neoplasms
- Tissue Adhesions
- Malignant Neoplasms
- Tumor Angiogenesis
- Cell Invasion
- Carcinoma
- Neoplasm Metastasis
- Rheumatoid Arthritis
- Arthritis
- Metastatic Malignant Neoplasm To The Lymph Node
- Cell Transformation, Neoplastic
- Melanoma
Interacting Proteins
- ITGB3
- ITGB5
- ITGB6
Pathways
- Angiogenesis
- Cell Adhesion
- Cell Proliferation
- Cell Cycle
- Cell-matrix Adhesion
- Integrin Activation
- Pathogenesis
- Osteoblast Differentiation
- Tube Formation
- Immune Response
- Vasculogenesis
- Embryo Development
- Platelet Aggregation
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ITGAV
bosterbio.com/bosterbio-gene-info-cards/ITGAV
References
PMID: 2443500 by Suzuki S., et al. Amino acid sequence of the vitronectin receptor alpha subunit and comparative expression of adhesion receptor mRNAs.
PMID: 10965141 by Sims M.A., et al. Cloning and characterisation of ITGAV, the genomic sequence for human cell adhesion protein (vitronectin) receptor alpha subunit, CD51.
9 Publications of Boster Integrin alpha-V Antibodies & ELISA Kits
- PubMed ID: 10.3390/ijms12063409, Study on the Expression and Clinical Significances of Lewis y Antigen and Integr...
- PubMed ID: 10.1038/srep20587, TGFβ3-mediated induction of Periostin facilitates head and neck cancer growth a...
- PubMed ID: 10.1002/ar.21398, Overexpression of Lewis (y) Antigen Protects Ovarian Cancer RMG‐1 Cells from C...
- PubMed ID: 10.1002/ar.21398, Overexpression of Lewis (y) Antigen Protects Ovarian Cancer RMG‐1 Cells from C...
- PubMed ID: 10.1002/ar.21398, Overexpression of Lewis (y) Antigen Protects Ovarian Cancer RMG‐1 Cells from C...
- PubMed ID: 21747684, Study on the Expression and Clinical Significances of Lewis y Antigen and Integr...
- PubMed ID: 26857387, TGF?3-mediated induction of Periostin facilitates head and neck cancer growth an...
- PubMed ID: 29312560, Xuan J, Chen Y, Zhu L, Guo Y, Deng L, Zheng Y, Wang Z, Wang Z, Ao M. Oncotarget....
- PubMed ID: 25666351, Chen Q, Zhang Z, Liu J, He Q, Zhou Y, Shao G, Sun X, Cao X, Gong A, Jiang P. Mol...
*More publications can be found for each product on its corresponding product page