Anti-IRAK2 Antibody

IRAK2 antibody

Boster Bio Anti-IRAK2 Antibody catalog # PA2236. Tested in IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: PA2236
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IHC, ICC, WB

Product Name

Anti-IRAK2 Antibody

View all IRAK2 Antibodies

SKU/Catalog Number

PA2236

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-IRAK2 Antibody catalog # PA2236. Tested in IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-IRAK2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2236)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human IRAK2, different from the related rat sequence by one amino acid, and from the related mouse sequence by three amino acids.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA2236 is reactive to IRAK2 in Human, Mouse, Rat

Applications

PA2236 is guaranteed for IHC, ICC, WB Boster Guarantee

Observed Molecular Weight

60 kDa

Calculated molecular weight

69.433kDa

Background of IRAK2

Interleukin-1 receptor-associated kinase-like 2 is an enzyme that in humans is encoded by the IRAK2 gene. This gene is mapped to 3p25.3. IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB. It binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunocytochemistry , 0.5-1μg/ml, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat, By Heat
Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat

Validation Images & Assay Conditions

Gene/Protein Information For IRAK2 (Source: Uniprot.org, NCBI)

Gene Name

IRAK2

Full Name

Interleukin-1 receptor-associated kinase-like 2

Weight

69.433kDa

Superfamily

protein kinase superfamily

Alternative Names

interleukin-1 receptor associated kinase-2; interleukin-1 receptor-associated kinase 2; interleukin-1 receptor-associated kinase-like 2; IRAK2; IRAK-2; MGC150550 IRAK2 IRAK-2 interleukin 1 receptor associated kinase 2 interleukin-1 receptor-associated kinase-like 2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on IRAK2, check out the IRAK2 Infographic

IRAK2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for IRAK2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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1 Customer Q&As for Anti-IRAK2 Antibody

Question

We are currently using anti-IRAK2 antibody PA2236 for rat tissue, and we are satisfied with the ICC results. The species of reactivity given in the datasheet says human, mouse, rat. Is it possible that the antibody can work on monkey tissues as well?

A. Collins

Verified customer

Asked: 2015-03-16

Answer

The anti-IRAK2 antibody (PA2236) has not been tested for cross reactivity specifically with monkey tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in monkey you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2015-03-16

Order DetailsPrice
PA2236

100μg

$370
PA2236-10ug

10μg sample (liquid)

$99
PA2236-Biotin

100 μg Biotin conjugated

$570
PA2236-Cy3

100 μg Cy3 conjugated

$570
PA2236-Dylight488

100 μg Dylight488 conjugated

$570
PA2236-Dylight550

100 μg Dylight550 conjugated

$570
PA2236-Dylight594

100 μg Dylight594 conjugated

$570
PA2236-FITC

100 μg FITC conjugated

$570
PA2236-HRP

100 μg HRP conjugated

$570
PA2236-APC

100 μg APC conjugated

$670
PA2236-PE

100 μg PE conjugated

$670
PA2236-carrier-free

Carrier Free

$370

More conjugates/formats

Free Secondary Antibody

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PA2236
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

Troubleshooting

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