IRAK2 Antibodies

AND IRAK2 ELISA kits, IRAK2 Proteins

Many biological assays use antibodies to detect IRAK2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IRAK2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IRAK2 antibodies...

We validate the specificity of these antibodies to IRAK2 by testing them on tissues known to express IRAK2 positively and negatively. Browse below to find the IRAK2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for IRAK2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the IRAK2 Western Blot Guide

IRAK2 Infographic by Boster Bio

All IRAK2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-IRAK2 Rabbit Monoclonal Antibody

Western blot analysis of IRAK2 expression in HeLa cell lysate

Human

Flow Cytometry, IP, WB

$370
Cat # M01559-1
100 μl/vial

Anti-IRAK2 Antibody Picoband®

IHC analysis of IRAK2 using anti-IRAK2 antibody (A01559)

Flow Cytometry analysis of U937 cells using anti-IRAK2 antibody (A01559)

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A01559
100 μg/vial

Anti-IRAK2 Antibody Picoband®

Anti-IRAK2 antibody, PA2236, Western blottingLane 1: 22RV Cell LysateLane 2: A549 Cell LysateLane 3: PANC Cell LysateLane 4: SMMC Cell Lysate

Anti-IRAK2 antibody, PA2236, IHC(P)IHC(P): Human Lung Cancer Tissue

Anti-IRAK2 antibody, PA2236, IHC(P)IHC(P): Rat Spleen Tissue

Human, Mouse, Rat

IHC, ICC, WB

$370
Cat # PA2236
100 μg/vial

Anti-IRAK2 Mouse Monoclonal Antibody [Clone ID: OTI4C1]

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-IRAK2 mouse monoclonal antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IRAK2 (Right lane) cDNA for 48 hrs and lysed

Human

IHC, WB

$523
Cat # M01559
100 µl

IRAK2 Overview

Facts about Interleukin-1 receptor-associated kinase-like 2.

IRAK2 3D structure. Source: alphafold

Interleukin-1 receptor-associated kinase-like 2 (IRAK2)

Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. .

Gene Information

Human
Gene Name:	IRAK2
Uniprot:	O43187
Entrez:	3656

Family

Belongs to:

protein kinase superfamily

Alternative Names

interleukin-1 receptor associated kinase-2; interleukin-1 receptor-associated kinase 2; interleukin-1 receptor-associated kinase-like 2; IRAK2; IRAK-2; MGC150550

Molecular Weight

Mass (kDA):
69.433 kDA

Genomic Context


Human

Location:	3p25.3
Sequence:	3; NC_000003.12 (10164919..10243745)

Tissue Specificity

Expressed in spleen, thymus, prostate, lung, liver, skeletal muscle, kidney, pancreas and peripheral blood leukocytes.

Diseases

Inflammation
Innate Immune Response
Malignant Neoplasms
Neoplasms
Vaccinia
Inflammatory Response
Infective Disorder
Carcinoma
Bacterial Infections
Liver Carcinoma
Asthma
Cell Invasion

Systemic Infection
Disease Of Adrenal Medulla
Malignant Neoplasm Of Breast
Hepatitis B
Myeloid Leukemia, Chronic
Neoplasm Invasiveness

Interacting Proteins

ARAF
IRAK4
Sarm1
STT3A
TARDBP

TIRAP
TOLLIP
TRAF6
ZC3H12A

Pathways

Immune Response
Innate Immune Response
Secretion
Chemokine Production
Inflammatory Response
Cytokine Production
Translation
Cell Cycle
Cell Death
Protein Phosphorylation
Toll-like Receptor Signaling Pathway
Induction Of Apoptosis

Cell Development
Signalosome Assembly
Virulence
Cell Cycle Arrest
Methylation
Reverse Transcription
Phagocytosis

PTMs

Phosphorylation

Methylation

Ubiquitination

Research Areas

Immunology
Innate Immunity
Protein Kinase
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IRAK2

References

PMID: 9374458 by Muzio M., et al. IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling.

PMID: 10383454 by Wesche H., et al. IRAK-M is a novel member of the Pelle/interleukin-1 receptor- associated kinase (IRAK) family.