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Product Info Summary
| SKU: | A00445 |
|---|---|
| Size: | 50 µl |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | IP, IHC, WB |
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Product info
Product Name
Anti-ITRAF TANK Antibody
SKU/Catalog Number
A00445
Size
50 µl
Form
Liquid
Description
Boster Bio Anti-ITRAF TANK Antibody (Catalog# A00445). Tested in IP, IHC, WB application(s). This antibody reacts with Human.
Storage & Handling
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Cite This Product
Anti-ITRAF TANK Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00445)
Host
Rabbit
Contents
50 μl sera
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide of human ITRAF (amino acids 346-367 DPSDAPFPSLDSPGKAIRGPQQ)
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
(ELISA)Recombinant canine CCL3 Weak
(ELISA)Recombinant equine CCL3 None
(ELISA)Recombinant mouse CCL3 None
(ELISA)Recombinant rabbit CCL3 None
Reactive Species
A00445 is reactive to TANK in Human
Applications
A00445 is guaranteed for IP, IHC, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
47.816kDa
Background of TANK
ARHGAP22 is a Rho GTPase-activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis. It acts as a GTPase activator for RAC1 by converting it to an inactive GDP-bound state and also inhibits RAC1-dependent lamellipodia formation. It may also play a role in transcription regulation via its interaction with VEZF1, by regulating activity of the endothelin-1 (EDN1) promoter. Anti-ARHGAP22 [p Ser22] antibody is ideal for researchers interested in Diabetes Research, Lipid and Metabolism research.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:1000-1:2000
IHC (paraffin): 1:1000-1:5000
IHC (frozen): Users should optimize
IP: 1:50-1:200
Validation Images & Assay Conditions
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Immunohistochemical analysis of TANK/I-TRAF1 expression in formalin-fixed, paraffin-embedded normal human colon using primary antibody dilution ratio of 1:2000. A-A3, low and high magnification images. Hematoxylin-eosin counterstain.
Protein Target Info & Infographic
Gene/Protein Information For TANK (Source: Uniprot.org, NCBI)
Gene Name
TANK
Full Name
TRAF family member-associated NF-kappa-B activator
Weight
47.816kDa
Alternative Names
ITRAF; I-TRAF; I-TRAFTRAF2; TANK; TRAF family member-associated NF-kappa-B activator; TRAF family member-associated NFKB activator; TRAF-interacting protein TANK I-TRAF, ITRAF, TRAF2 TRAF family member associated NFKB activator TRAF family member-associated NF-kappa-B activator|TRAF-interacting protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TANK, check out the TANK Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TANK: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ITRAF TANK Antibody (A00445)
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No publications found for A00445
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Customer Reviews
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