Anti-JAM A pY280 F11R Antibody

JAM-A antibody

Boster Bio Anti-JAM A pY280 F11R Antibody (Catalog # A02068). Tested in ELISA, IF, WB applications. This antibody reacts with Human.

Product Info Summary

SKU: A02068
Size: 100ug
Reactive Species: Human
Host: Rabbit
Application: ELISA, IF, WB

Product Name

Anti-JAM A pY280 F11R Antibody

View all JAM-A Antibodies

SKU/Catalog Number

A02068

Size

100ug

Form

Liquid (sterile filtered)

Description

Boster Bio Anti-JAM A pY280 F11R Antibody (Catalog # A02068). Tested in ELISA, IF, WB applications. This antibody reacts with Human.

Storage & Handling

Store vial at -20°C prior to opening.  Aliquot contents and freeze at -20°C or below for extended storage.  Avoid cycles of freezing and thawing.  Centrifuge product if not completely clear after standing at room temperature.  This product is stable for several weeks at 4°C as an undiluted liquid.  Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.

Cite This Product

Anti-JAM A pY280 F11R Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02068)

Host

Rabbit

Contents

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01% (w/v) Sodium Azide

Clonality

Polyclonal

Isotype

IgG

Immunogen

Affinity purified Anti-JAM A pY280 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the c-term and phosphorylated at the tyrosine 280 position of Human JAM A protein.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A02068 is reactive to F11r in Human

Applications

A02068 is guaranteed for ELISA, IF, WB Boster Guarantee

Observed Molecular Weight

42 kDa

Calculated molecular weight

32.424kDa

Background of JAM-A

Anti-JAM A pY280 was designed, produced, and validated as part of the Joy Cappel Young Investigator Award (JCYIA). JAM A pY280 Antibody detects junctional adhesion molecule A (JAM A) protein phosphorylated at the tyrosine 280 location. JAM A is involved in cell-cell contact and tight junction formation in epithelial cells. JAM A protein is a transmembrane protein expressed in epithelial and endothelial cells as well as in hematopoietic cells and is important for a variety of cellular processes including tight junction assembly, leukocyte transmigration, platelet activation, angiogenesis and virus binding. In addition, JAM A may be a potential therapeutic target for breast cancer.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Restore with deionized water (or equivalent) for reconstitution volume of 100 µL

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

ELISA: 5 ug/ml
IF Microscopy: User optimized
WB: 1 ug/ml

Validation Images & Assay Conditions

Gene/Protein Information For F11r (Source: Uniprot.org, NCBI)

Gene Name

F11r

Full Name

Junctional adhesion molecule A

Weight

32.424kDa

Superfamily

immunoglobulin superfamily

Alternative Names

CD321 antigen; CD321; F11 receptor; F11R; JAM-1; JAM1CD321; JAMA; JAM-A; JCAMJAM; Junctional adhesion molecule 1Platelet F11 receptor; junctional adhesion molecule A; PAM-1; PAM-1KAT; Platelet adhesion molecule 1 F11r|9130004G24, AA638916, ESTM3, ESTM33, JAM, JAM-, JAM-1, JAM-A, Jcam, Jcam1, Ly10, Ly106|F11 receptor|junctional adhesion molecule A|BV11 antigen|F11 receptor/F11R|junction cell adhesion molecule A|junction cell adhesion molecule1|junctional adhesion molecule 1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on F11r, check out the F11r Infographic

F11r infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for F11r: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A02068

100 μg

$599

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