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Product Info Summary
| SKU: | A11010-1 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Rat |
| Host: | Rabbit |
| Application: | ELISA, IHC-P, WB |
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Product info
Product Name
Anti-Kelch-like protein 1 KLHL1 Antibody
SKU/Catalog Number
A11010-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Kelch-like protein 1 KLHL1 Antibody (Catalog # A11010-1). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Rat.
Storage & Handling
KLHL1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Kelch-like protein 1 KLHL1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A11010-1)
Host
Rabbit
Contents
KLHL1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
KLHL1 antibody was raised against a 14 amino acid synthetic peptide from near the amino-terminus of human KLHL1. The immunogen is located within the first 50 amino acids of KLHL1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least three isoforms of MTERFD1 are known to exist. MTERFD1 antibody is predicted to not cross-react with other MTERFD protein family members.
Reactive Species
A11010-1 is reactive to KLHL1 in Human, Rat
Applications
A11010-1 is guaranteed for ELISA, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
82.68kDa
Background of KLHL1
The mammalian Kelch-like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin-organizing proteins. Based on the presence of anti-sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8), it has been suggested that KLHL1 is involved this disease and that regulation of KLHL1 protein may be affected by antisense RNA expression.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
KLHL1 antibody can be used for the detection of KLHL1 by Western blot at 2 - 4 μg/mL. Antibody can also be used for immunohistochemistry starting at 10 μg/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of KLHL1 in HeLa cell lysate with KLHL1 antibody at (A) 2 and (B) 4 μg/mL.
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Immunohistochemistry of KLHL1 in rat brain tissue with KLHL1 antibody at 10 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For KLHL1 (Source: Uniprot.org, NCBI)
Gene Name
KLHL1
Full Name
Kelch-like protein 1
Weight
82.68kDa
Alternative Names
FLJ30047; kelch (Drosophila)-like 1; kelch-like 1 (Drosophila); KIAA1490kelch-like protein 1; Mayven-related protein 2; MRP2 KLHL1 MRP2 kelch like family member 1 kelch-like protein 1|Mayven-related protein 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on KLHL1, check out the KLHL1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for KLHL1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Kelch-like protein 1 KLHL1 Antibody (A11010-1)
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No publications found for A11010-1
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