Product Info Summary
SKU: | A01934 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IF, IHC, ICC, WB |
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Product info
Product Name
Anti-Kinesin-1 heavy chain KIF5B Antibody
View all Kinesin 5B Antibodies
SKU/Catalog Number
A01934
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Kinesin-1 heavy chain KIF5B Antibody catalog # A01934. Tested in WB,IHC,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Kinesin-1 heavy chain KIF5B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01934)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Bamacan (Phospho-Ser1083)
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A01934 is reactive to KIF5B in Human, Mouse, Rat
Applications
A01934 is guaranteed for IF, IHC, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
109.685kDa
Background of Kinesin 5B
Cullins assemble a potentially large number of ubiquitin ligases by binding to the RING protein ROC1 to catalyse polyubiquitination, as well as binding to various specificity factors to recruit substrates. Cullin 5 is a component of E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Cullin 5 seems to be involved proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. Cullin 5 may form a cell surface vasopressin receptor. Cullin 5 is part of a E3 ubiquitin ligase complex with elongin BC complex (TCEB1 and TCEB2), RBX1 and MUF1, complexes with elongin BC complex (TCEB1 and TCEB2), RXB1 and TCEB3 or SOCS1 or WSB1; elongin BC complex (TCEB1 and TCEB2), RBX1 and VHL; elongin BC complex (TCEB1 and TCEB2), RBX1, adenovirus type 5 E1B-55kDa protein and adenovirus type 5 E4-orf6. Cullin 5 Interacts with RBX1 and RNF7.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IHC: 1:50-1:100
ICC/IF: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-Kinesin-1 heavy chain KIF5B Antibody A01934
Western blot analysis of extracts of various cell linesProtein Target Info & Infographic
Gene/Protein Information For KIF5B (Source: Uniprot.org, NCBI)
Gene Name
KIF5B
Full Name
Kinesin-1 heavy chain
Weight
109.685kDa
Superfamily
TRAFAC class myosin-kinesin ATPase superfamily
Alternative Names
Conventional kinesin heavy chain; kinesin family member 5B; kinesin-1 heavy chain; KNS1kinesin 1 (110-120kD); KNSKINH; Ubiquitous kinesin heavy chain; UKHCkinesin heavy chain KIF5B HEL-S-61, KINH, KNS, KNS1, UKHC kinesin family member 5B kinesin-1 heavy chain|conventional kinesin heavy chain|epididymis secretory protein Li 61|kinesin 1 (110-120kD)|kinesin heavy chain|ubiquitous kinesin heavy chain
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on KIF5B, check out the KIF5B Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for KIF5B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Kinesin-1 heavy chain KIF5B Antibody (A01934)
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No publications found for A01934
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