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Product Info Summary
| SKU: | A05508 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-LAMTOR2 Antibody
SKU/Catalog Number
A05508
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-LAMTOR2 Antibody (Catalog # A05508). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
LAMTOR2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-LAMTOR2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05508)
Host
Rabbit
Contents
LAMTOR2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
LAMTOR2 antibody was raised against an 18 amino acid peptide near the center of human LAMTOR2. The immunogen is located within amino acids 40 - 90 of LAMTOR2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
LAMTOR2 antibody is human, mouse and rat reactive. At least two isoforms of LAMTOR2 are known to exist; this antibody will detect both isoforms. LAMTOR2 antibody is predicted to not cross-react with other LAMTOR family proteins.
Reactive Species
A05508 is reactive to LAMTOR2 in Human, Mouse, Rat
Applications
A05508 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
13.508kDa
Background of ROBLD3
The late endosomal/lysosomal adaptor MAPK and MTOR activator 2 (LAMTOR2) protein belongs to the LAMTOR family of proteins, and together with LAMTOR3 and the MAPK1 and ERK kinase 1 (MEK1) localizes to late endosomes where it is required for the efficient activation of ERK signaling (1,2). This complex is involved in the regulation of late endosomal traffic and cellular proliferation (3) and plays a role in cellular host defense against Salmonella infection (4).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
LAMTOR2 antibody can be used for detection of LAMTOR2 by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of LAMTOR2 in HepG2 cell lysate with LAMTOR2 antibody at 1 μg/ml.
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Immunohistochemistry of LAMTOR2 in human spleen tissue with LAMTOR2 antibody at 5 μg/mL.
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Immunofluorescence of LAMTOR2 in human spleen tissue with LAMTOR2 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For LAMTOR2 (Source: Uniprot.org, NCBI)
Gene Name
LAMTOR2
Full Name
Ragulator complex protein LAMTOR2
Weight
13.508kDa
Superfamily
GAMAD family
Alternative Names
ENDAP; Endosomal adaptor protein p14; HSPC003; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2; late endosomal/lysosomal adaptor, MAPK and MTOR activator 2; Late endosomal/lysosomal Mp1-interacting protein; MAPBPIPRoadblock domain-containing protein 3; MAPKSP1 adaptor protein; MAPKSP1AP; mitogen-activated protein-binding protein-interacting protein (MAPBPIP); Mitogen-activated protein-binding protein-interacting protein; p14Ragulator2; roadblock domain containing 3; ROBLD3 LAMTOR2 ENDAP, HSPC003, MAPBPIP, MAPKSP1AP, ROBLD3, Ragulator2, p14 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 ragulator complex protein LAMTOR2|MAPBP-interacting protein|MAPKSP1 adaptor protein|endosomal adaptor protein p14|late endosomal/lysosomal Mp1-interacting protein|late endosomal/lysosomal adaptor and MAPK and MTOR activator 2|mitogen-activated protein-binding protein-interacting protein (MAPBPIP)|roadblock domain containing 3|roadblock domain-containing protein 3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on LAMTOR2, check out the LAMTOR2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for LAMTOR2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-LAMTOR2 Antibody (A05508)
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