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Product Info Summary
| SKU: | A08040 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-LAMTOR3 Antibody
SKU/Catalog Number
A08040
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-LAMTOR3 Antibody (Catalog # A08040). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
LAMTOR3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-LAMTOR3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08040)
Host
Rabbit
Contents
LAMTOR3 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
LAMTOR3 antibody was raised against an 15 amino acid peptide near the center of human LAMTOR3. The immunogen is located within amino acids 40 - 90 of LAMTOR3.
Cross-reactivity
LAMTOR3 antibody is human, mouse and rat reactive. At least two isoforms of LAMTOR3 are known to exist; this antibody will detect both isoforms. LAMTOR3 antibody is predicted to not cross-react with other LAMTOR family proteins.
Reactive Species
A08040 is reactive to LAMTOR3 in Human, Mouse, Rat
Observed Molecular Weight
68 kDa
Calculated molecular weight
13.6 kDa
Background of LAMTOR3
The late endosomal/lysosomal adaptor MAPK and MTOR activator 3 (LAMTOR3) protein belongs to the LAMTOR family of proteins, and together with LAMTOR2 and the MAPK1 and ERK kinase 1 (MEK1) localizes to late endosomes where it is required for the efficient activation of ERK signaling (1,2). This complex is involved in the regulation of late endosomal traffic and cellular proliferation (3) and plays a role in cellular host defense against Salmonella infection (4).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A08040 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
LAMTOR3 antibody can be used for detection of LAMTOR3 by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of LAMTOR3 in human brain tissue lysate with LAMTOR3 antibody at (A) 1 and (B) 2 μg/ml
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Immunohistochemistry of LAMTOR3 in human brain tissue with LAMTOR3 antibody at 5 μg/mL.
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Immunofluorescence of LAMTOR3 in human brain tissue with LAMTOR3 antibody at 20 μg/mL.
Specific Publications For Anti-LAMTOR3 Antibody (A08040)
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