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Product Info Summary
| SKU: | A06363 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IHC-P, WB |
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Product info
Product Name
Anti-LZTR1 Antibody
SKU/Catalog Number
A06363
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-LZTR1 Antibody (Catalog # A06363). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
LZTR1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-LZTR1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06363)
Host
Rabbit
Contents
LZTR1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
LZTR1 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human LZTR1. The immunogen is located within amino acids 130 - 180 of LZTR1.
Reactive Species
A06363 is reactive to LZTR1 in Human, Mouse, Rat
Observed Molecular Weight
68 kDa
Calculated molecular weight
94.7 kDa
Background of LZTR1
LZTR1, a member of the BTB-kelch superfamily, was initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Golgi complex. Deletion of this gene may be associated with DiGeorge syndrome, a developmental field defect involving the third and fourth pharyngeal pouches, causing the absence of thymus and parathyroid glands, congenital cardiac abnormalities and facial dysmorphism. LZTR1 is tyrosine phosphorylated and subsequently degraded upon induction of apoptosis.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A06363 is guaranteed for ELISA, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
LZTR1 antibody can be used for detection of LZTR1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of LZTR1 in human heart tissue lysate with LZTR1 antibody at (A) 1 and (B) 2 μg/mL.
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Immunohistochemistry of LZTR1 in mouse heart tissue with LZTR1 antibody at 5 μg/mL.
Specific Publications For Anti-LZTR1 Antibody (A06363)
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