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Product Info Summary
| SKU: | A01599 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-MALT1 Antibody
SKU/Catalog Number
A01599
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-MALT1 Antibody (Catalog # A01599). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
MALT1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-MALT1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01599)
Host
Rabbit
Contents
MALT1 antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
MALT1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human MALT1. The immunogen is located within amino acids 630 - 680 of MALT1.
Cross-reactivity
MALT1 antibody is human, mouse and rat reactive. At least two isoforms of MALT1 are known to exist; this antibody will detect both isoforms.
Reactive Species
A01599 is reactive to MALT1 in Human, Mouse, Rat
Observed Molecular Weight
68 kDa
Calculated molecular weight
92.3 kDa
Background of MALT1
MALT1 was initially identified as a novel gene that was recurrently rearranged in t(11;18)(q21;q21) mucosa-associated lymphoid tissue lymphomas along with the apoptosis inhibitor protein c-IAP2 (1). MALT1, along with the proteins CARMA1 and Bcl10 form an NF-kappaB-activating complex, termed the CBM signalsome, that acts downstream of lymphocyte antigen receptors as well as many other non-lymphoid cell-surface receptors that play a role in multiple cellular functions (2,3). MALT1 has proteolytic activity, and this activity is critical for full NF-kappaB response in T cell activation (4).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A01599 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
MALT1 antibody can be used for detection of MALT1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of MALT1 in EL4 cell lysate with MALT1 antibody at (A) 1 and (2) μg/ml.
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Immunohistochemistry of MALT1 in human spleen tissue with MALT1 antibody at 5 μg/mL.
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Immunofluorescence of MALT1 in human spleen tissue with MALT1 antibody at 20 μg/mL.
Specific Publications For Anti-MALT1 Antibody (A01599)
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