|Ig Isotype||Mouse IgG1|
|Product Name||Anti-MAP1 Antibody (Monoclonal, HM-1)|
|Storage & Handling||At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.|
|Description||Mouse IgG monoclonal antibody for MAP1, microtubule-associated protein 1A (MAP1A) detection. Tested with WB, IHC-P, IHC-F in Mouse;rat. No cross reactivity with other proteins.|
|Cite This Product||Anti-MAP1 Antibody (Monoclonal, HM-1) (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1056)|
|Contents/Buffer||Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.|
|Immunogen||Rat brain microtubule-associated proteins(MAPs).|
Assay Dilutions Overview
Immunohistochemistry(Paraffin-embedded Section), 1-2μg/ml, Mouse, rat, By Heat
Immunohistochemistry(Frozen Section), 1-2μg/ml, Mouse, rat, -
Western blot, 0.5-2μg/ml, Mouse, rat
Boster's Secondary Antibodies And IHC, WB Kits
The following reagents are used to generate the images below.Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P) and IHC(F).
Images And Assay Conditions
Anti-MAP1 antibody (monoclonal), MA1056, IHC(P)
IHC(P): Rat Brain Tissue
Protein Target Info (Source: Uniprot.org)
|Protein Name||Microtubule-associated protein 1A|
|Tissue Specificity||Brain, heart and muscle.|
|Alternative Names||Microtubule-associated protein 1A;MAP-1A;MAP1A heavy chain;MAP1 light chain LC2;Map1a;Mtap1a;|
|Subcellular Localization||Cytoplasm, cytoskeleton .|
|Molecular Weight||299531 MW|
*if product is indicated to react with multiple species, protein info is based on the human gene.
|Protein Function||Structural protein involved in the filamentous cross- bridging between microtubules and other skeletal elements.|
|Research Areas||Cytoskeleton, Cytoskeleton / Ecm, Microtubules, Neurogenesis, Neurology Process, Neuroscience, Signal Transduction
*You can search these to find other products in these research areas.
|Background||Microtubules are the ubiquitous cytoskeletal structural components that are involved in intracellular transport. They are composed of tubulin and microtubule-associated proteins(MAPs). MAP1 is one of the major neuronal MAPs as well as being the largest(350KD). MAPs include MAP1A, MAP1B, and MAP2. MAP1a is a single-copy gene spanning 10.5 kb. MAP1a coding sequence is contained in five exons. MAP1B is encoded as a polyprotein that is processed to form a complex N-terminal microtubule-binding domain.|
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