Anti-MARK3 Antibody

Product Name

Anti-MARK3 Antibody

View all MARK3 Antibodies

SKU/Catalog Number

A05355

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-MARK3 Antibody (Catalog # A05355). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-MARK3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05355)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from N-terminal of human MARK3.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A05355 is reactive to MARK3 in Human, Mouse, Rat

Applications

A05355 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

111 kDa

Calculated molecular weight

84.429kDa

Background of MARK3

Involved in the specific phosphorylation of microtubule-associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus.

Peng C.Y., Cell Growth Differ. 9:197-208(1998).
Sun T.-Q., Nat. Cell Biol. 3:628-636(2001).
Wissing J., Mol. Cell. Proteomics 6:537-547(2007)

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Validation Images & Assay Conditions

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Western blot analysis of extracts from HeLa cells and 293 cells, using MARK3 antibody A05355.

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Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using MARK3 antibody A05355.

Gene/Protein Information For MARK3 (Source: Uniprot.org, NCBI)

Alternative Names

Cdc25C-associated protein kinase 1; cTAK1; C-TAK1; CTAK1ELKL motif kinase 2; EC 2.7.11; EC 2.7.11.1; EMK2; EMK-2; KP78; MAP/microtubule affinity-regulating kinase 3; PAR1A; Protein kinase STK10; Ser/Thr protein kinase PAR-1; Serine/threonine-protein kinase p78 MARK3 CTAK1, KP78, PAR1A, Par-1a, VIPB microtubule affinity regulating kinase 3 MAP/microtubule affinity-regulating kinase 3|C-TAK1|ELKL motif kinase 2|EMK-2|cdc25C-associated protein kinase 1|protein kinase STK10|ser/Thr protein kinase PAR-1|serine/threonine-protein kinase p78

For more info on MARK3, check out the MARK3 Infographic

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In this infographic, you will see the following information for MARK3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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