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Product Info Summary
| SKU: | A33936 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-MFSD2A Antibody
SKU/Catalog Number
A33936
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-MFSD2A Antibody (Catalog # A33936). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
MFSD2A antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-MFSD2A Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A33936)
Host
Rabbit
Contents
MFSD2A Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
MFSD2A antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human MFSD2A. The immunogen is located within the last 50 amino acids of MFSD2A.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least three isoforms of KLRA1 are known to exist; this antibody recognizes only the long isoform.
Reactive Species
A33936 is reactive to in Human, Mouse, Rat
Applications
A33936 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
31311 MW
Background of
Multidrug transporters, such as MFSD2A, are membrane proteins that expel a wide spectrum of cytotoxic compounds from the cell and render cells resistant to multiple drugs. Major Facilitator Superfamily (MFS) members are capable of transporting various substrates such as sugars, polyols, drugs, neurotransmitters, amino acids, peptides, and inorganic anions, although most members are substrate-specific. MFSD2A is a novel lung cancer tumor suppressor gene that regulates cell cycle progression and matrix attachment and has recently been described as the human receptor for syncytin-2, a retrovirus-derived protein mediating fusion of placental trophoblasts. MFSD2A is expressed in many tissues and is highly induced in liver and brown adipose tissue (BAT) during fasting. The activation of the betaAR signaling pathway plays a major role in the induction of MFSD2A expression during adaptive thermogenesis.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
MFSD2A antibody can be used for detection of MFSD2A by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in human, mouse, and rat samples and Immunofluorescence in mouse and rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of MFSD2A in rat lung tissue lysate with MFSD2A antibody at (A) 1 and (B) 2 μg/mL.
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Immunohistochemistry of MFSD2A in mouse lung tissue with MFSD2A antibody at 2.5 μg/ml.
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Immunofluorescence of MFSD2A in Rat Lung cells with MFSD2A antibody at 20 μg/mL.
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Immunohistochemistry of MFSD2A in rat lung tissue with MFSD2A antibody at 5 μg/mL.
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Immunofluorescence of MFSD2A in mouse lung tissue with MFSD2A antibody at 20 μg/mL.
Red: MFSD2A Antibody (A33936)
Blue: DAPI staining
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Immunohistochemistry of MFSD2A in human brain tissue with MFSD2A antibody at 5 μg/mL.
Specific Publications For Anti-MFSD2A Antibody (A33936)
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Customer Reviews
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