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Product Info Summary
| SKU: | A01338-2 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IF, IHC, WB |
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Product info
Product Name
Anti-mGluR-5 (K56) GRM5 Antibody
SKU/Catalog Number
A01338-2
Size
100ul
Form
Liquid
Description
Boster Bio Anti-mGluR-5 (K56) GRM5 Antibody catalog # A01338-2. Tested in WB,IHC,IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-mGluR-5 (K56) GRM5 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01338-2)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human NCoA-3.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01338-2 is reactive to GRM5 in Human, Mouse, Rat
Applications
A01338-2 is guaranteed for IF, IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
132.469kDa
Background of GRM5
The NCOA3 (also known as nuclear receptor coactivator 3 isoform a) is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions in a hormone-dependent fashion. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. NCOA3 probably acts via remodeling of chromatin and is involved in the coactivation of different nuclear receptors, such as for steroids (GR and ER), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). NCOA3 is also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFKB1 subunit. NCOA3 may be associated with diseases such as breast cancer and meningothelial meningioma. Anti-NCOA3 Antibody is useful for researchers interested in cancer research, chromatin binding, transcription coactivator activity, Immunology, and Nuclear Signaling research.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
IHC: 1:50-1:200
IF: 1:50-1:200
Validation Images & Assay Conditions
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Protein Target Info & Infographic
Gene/Protein Information For GRM5 (Source: Uniprot.org, NCBI)
Gene Name
GRM5
Full Name
Metabotropic glutamate receptor 5
Weight
132.469kDa
Superfamily
G-protein coupled receptor 3 family
Alternative Names
glutamate receptor, metabotropic 5; GPRC1EMGLUR5metabotropic glutamate receptor 5; mGlu5; mGluR5 GRM5 GPRC1E, MGLUR5, PPP1R86, mGlu5 glutamate metabotropic receptor 5 metabotropic glutamate receptor 5|glutamate receptor, metabotropic 5|protein phosphatase 1, regulatory subunit 86
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on GRM5, check out the GRM5 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for GRM5: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-mGluR-5 (K56) GRM5 Antibody (A01338-2)
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No publications found for A01338-2
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