Anti-Mitofilin IMMT Antibody

Product Name

Anti-Mitofilin IMMT Antibody

View all Mitofilin Antibodies

SKU/Catalog Number

A04102

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Mitofilin IMMT Antibody catalog # A04102. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Mitofilin IMMT Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04102)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human IGFBP6.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A04102 is reactive to IMMT in Human, Mouse, Rat

Applications

A04102 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

83.678kDa

Background of Mitofilin

Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons By similarity.

Mitsutoshi Nakada, Cancer Res., Sep 2006; 66: 8492 - 8500.
Klas Kullander, Genes & Dev., Apr 2001; 15: 877.
M. Douglas Benson, PNAS, Jul 2005; 102: 10694 - 10699.
Stephanie R. Kadison, J. Neurosci., Aug 2006; 26: 8909 - 8914.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:1000

Validation Images & Assay Conditions

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Figure 1. Western blotting validation for Anti-Mitofilin IMMT Antibody A04102

Western blot (WB) analysis of Mitofilin polyclonal antibody at 1:500 dilution
Lane1:MCF-7 cell lysate
Lane2:sp2/0 cell lysate
Lane3:PC12 cell lysate
Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration

Gene/Protein Information For IMMT (Source: Uniprot.org, NCBI)

Alternative Names

DKFZp779P1653; inner membrane protein, mitochondrial; MGC111146; Mic 60; Mic60; MICOS Complex Subunit MIC60; mitochondrial (mitofilin); mitofilin; motor protein; p87/89; proliferation-inducing gene 4 IMMT HMP, MICOS60, MINOS2, Mic60, P87, P87/89, P89, PIG4, PIG52 inner membrane mitochondrial protein MICOS complex subunit MIC60|cell proliferation-inducing gene 4/52 protein|cell proliferation-inducing protein 52|heart muscle protein|mitochondrial contact site and cristae organizing system subunit 60|mitochondrial inner membrane organizing system 2|mitochondrial inner membrane protein|mitofilin|motor protein|proliferation-inducing gene 4

For more info on IMMT, check out the IMMT Infographic

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In this infographic, you will see the following information for IMMT: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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