Product Info Summary
SKU: | A06136 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IHC, WB |
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Product info
Product Name
Anti-MSRB2 Antibody
SKU/Catalog Number
A06136
Size
100ul
Form
Liquid
Description
Boster Bio Anti-MSRB2 Antibody catalog # A06136. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-MSRB2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06136)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human VHR.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A06136 is reactive to MSRB2 in Human, Mouse, Rat
Applications
A06136 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
19.536kDa
Background of MSRB2
Serine/threonine kinase which acts as a negative regulator of Ras-related Rap2-mediated signal transduction to control neuronal structure and AMPA receptor trafficking. Required for normal synaptic density, dendrite complexity, as well as surface AMPA receptor expression in hippocampal neurons. Can activate the JNK and MAPK14/p38 pathways and mediates stimulation of the stress-activated protein kinase MAPK14/p38 MAPK downstream of the Raf/ERK pathway. Phosphorylates: TANC1 upon stimulation by RAP2A, MBP and SMAD1. Has an essential function in negative selection of thymocytes, perhaps by coupling NCK1 to activation of JNK1. Isoform 4 can activate the JNK pathway. Involved in the regulation of actin cytoskeleton reorganization, cell-matrix adhesion, cell-cell adhesion and cell migration.
Dan I., FEBS Lett. 469:19-23(2000).
Beausoleil S.A., Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).
Olsen J.V., Cell 127:635-648(2006).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Reconsitution
Restore with deionized water (or equivalent) for reconstitution volume of 100 µL
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IHC: 1:50-1:100
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For MSRB2 (Source: Uniprot.org, NCBI)
Gene Name
MSRB2
Full Name
Methionine-R-sulfoxide reductase B2, mitochondrial
Weight
19.536kDa
Superfamily
MsrB Met sulfoxide reductase family
Alternative Names
CBS1; CBS-1methionine-r-sulfoxide reductase B2 variant 3; CGI-131; EC 1.8.4; EC 1.8.4.-; EC 1.8.4.12; methionine sulfoxide reductase B; methionine sulfoxide reductase B2; methionine-r-sulfoxide reductase B2 variant 1; methionine-R-sulfoxide reductase B2, mitochondrial; MGC26104; MSRB; MsrB2; PILB; pilin-like transcription factor MSRB2 CBS-1, CBS1, CGI-131, MSRB, PILB methionine sulfoxide reductase B2 methionine-R-sulfoxide reductase B2, mitochondrial|pilin-like transcription factor
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on MSRB2, check out the MSRB2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for MSRB2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-MSRB2 Antibody (A06136)
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No publications found for A06136
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