Product Info Summary
SKU: | A09972 |
---|---|
Size: | 100ul |
Reactive Species: | Human |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-Myosin-13 MYH13 Antibody
SKU/Catalog Number
A09972
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Myosin-13 MYH13 Antibody catalog # A09972. Tested in WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Myosin-13 MYH13 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09972)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human ABHDA protein.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A09972 is reactive to MYH13 in Human
Applications
A09972 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
223.605kDa
Background of MYH13
Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD+/NADP+ ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase. Its substrates are however unknown.
Yazaki M., Submitted (AUG-1996) to the EMBL/GenBank/DDBJ databases.
Ishikawa K., DNA Res. 4:307-313(1997).
The MGC Project Team; Genome Res. 14:2121-2127(2004).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:200-1:2000
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-Myosin-13 MYH13 Antibody A09972
Western blot analysis of extracts of various cell linesProtein Target Info & Infographic
Gene/Protein Information For MYH13 (Source: Uniprot.org, NCBI)
Gene Name
MYH13
Full Name
Myosin-13
Weight
223.605kDa
Superfamily
TRAFAC class myosin-kinesin ATPase superfamily
Alternative Names
Myosin-13 MYH13 MyHC-IIL, MyHC-eo myosin heavy chain 13 myosin-13|extraocular muscle myosin heavy chain|extraocular myosin heavy chain|myosin heavy chain, skeletal muscle, extraocular|myosin heavy chain, skeletal muscle, laryngeal|myosin, heavy chain 13, skeletal muscle|myosin, heavy polypeptide 13, skeletal muscle|superfast myosin
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on MYH13, check out the MYH13 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for MYH13: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Myosin-13 MYH13 Antibody (A09972)
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No publications found for A09972
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