Anti-Nipped-B-like protein NIPBL Antibody

NIPBL antibody

Boster Bio Anti-Nipped-B-like protein NIPBL Antibody catalog # A01939. Tested in IHC applications. This antibody reacts with Human, Mouse.

Product Info Summary

SKU: A01939
Size: 100ul
Reactive Species: Human, Mouse
Host: Rabbit
Application: IHC

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Product Name

Anti-Nipped-B-like protein NIPBL Antibody

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SKU/Catalog Number

A01939

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Nipped-B-like protein NIPBL Antibody catalog # A01939. Tested in IHC applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Nipped-B-like protein NIPBL Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01939)

Host

Rabbit

Contents

Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human NIPBL protein.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A01939 is reactive to NIPBL in Human, Mouse

Applications

A01939 is guaranteed for IHC Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

316.051kDa

Background of NIPBL

Cullins assemble a potentially large number of ubiquitin ligases by binding to the RING protein ROC1 to catalyse polyubiquitination, as well as binding to various specificity factors to recruit substrates. Cullin 5 is a component of E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Cullin 5 seems to be involved proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. Cullin 5 may form a cell surface vasopressin receptor. Cullin 5 is part of a E3 ubiquitin ligase complex with elongin BC complex (TCEB1 and TCEB2), RBX1 and MUF1, complexes with elongin BC complex (TCEB1 and TCEB2), RXB1 and TCEB3 or SOCS1 or WSB1; elongin BC complex (TCEB1 and TCEB2), RBX1 and VHL; elongin BC complex (TCEB1 and TCEB2), RBX1, adenovirus type 5 E1B-55kDa protein and adenovirus type 5 E4-orf6. Cullin 5 Interacts with RBX1 and RNF7.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

IHC-p 1:50-300

Validation Images & Assay Conditions

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Gene/Protein Information For NIPBL (Source: Uniprot.org, NCBI)

Gene Name

NIPBL

Full Name

Nipped-B-like protein

Weight

316.051kDa

Superfamily

SCC2/Nipped-B family

Alternative Names

CDLS1; delangin; DKFZp434L1319; FLJ11203; FLJ12597; FLJ13354; FLJ13648; FLJ44854; IDN3-B; IDN3CDLS; Nipped-B homolog (Drosophila); nipped-B-like protein; SCC2 homolog; Scc2; sister chromatid cohesion 2 homolog NIPBL CDLS, CDLS1, IDN3, IDN3-B, Scc2 NIPBL cohesin loading factor nipped-B-like protein|Nipped-B homolog|SCC2 homolog|delangin|sister chromatid cohesion 2 homolog

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on NIPBL, check out the NIPBL Infographic

NIPBL infographic

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In this infographic, you will see the following information for NIPBL: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A01939-100ul

100ul

$380

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