Product Info Summary
SKU: | A01136 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-P2Y purinoceptor 12 P2RY12 Antibody
View all P2Y12/P2RY12 Antibodies
SKU/Catalog Number
A01136
Size
100ul
Form
Liquid
Description
Boster Bio Anti-P2Y purinoceptor 12 P2RY12 Antibody catalog # A01136. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-P2Y purinoceptor 12 P2RY12 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01136)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human TTK around the phosphorylation site of T676.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01136 is reactive to P2ry12 in Human, Mouse, Rat
Applications
A01136 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
39.047kDa
Background of P2Y12/P2RY12
Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint.
Mills G.B., J. Biol. Chem. 267:16000-16006(1992).
Ota T., Nat. Genet. 36:40-45(2004).
Mungall A.J., Nature 425:805-811(2003)
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-P2Y purinoceptor 12 P2RY12 Antibody A01136
Western blot analysis of extracts of various cell linesProtein Target Info & Infographic
Gene/Protein Information For P2ry12 (Source: Uniprot.org, NCBI)
Gene Name
P2ry12
Full Name
P2Y purinoceptor 12
Weight
39.047kDa
Superfamily
G-protein coupled receptor 1 family
Alternative Names
ADPG-R; Gi-coupled ADP receptor HORK3; HORK3; HORK3P2Y12 platelet ADP receptor; P2RY12; P2T(AC); P2Y purinoceptor 12; P2Y(AC); P2Y(ADP); P2Y(cyc); P2Y12; P2Y12ADP-glucose receptor; purinergic receptor P2RY12; purinergic receptor P2Y, G-protein coupled, 12; putative G-protein coupled receptor; SP1999; SP1999G-protein coupled receptor SP1999 P2ry12|P2y12|purinergic receptor P2Y12|P2Y purinoceptor 12|P2Y12 platelet ADP receptor|purinergic receptor P2Y, G-protein coupled, 12
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on P2ry12, check out the P2ry12 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for P2ry12: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-P2Y purinoceptor 12 P2RY12 Antibody (A01136)
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No publications found for A01136
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