Anti-p63 TP63 Rabbit Monoclonal Antibody

Product Name

Anti-p63 TP63 Rabbit Monoclonal Antibody

View all p63/TP73L Antibodies

SKU/Catalog Number

M00167-1

Size

100 μl

Form

Liquid

Description

Boster Bio Anti-p63 TP63 Rabbit Monoclonal Antibody catalog # M00167-1. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-p63 TP63 Rabbit Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00167-1)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Clonality

Monoclonal

Clone Number

FCB-20

Isotype

Rabbit IgG

Immunogen

A synthesized peptide derived from human p63

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M00167-1 is reactive to TP63 in Human, Mouse, Rat

Applications

M00167-1 is guaranteed for Flow Cytometry, IF, IHC, ICC, WB Boster Guarantee

Observed Molecular Weight

30 kDa

Calculated molecular weight

76.785kDa

Background of p63/TP73L

Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4-phosphate) and PtdIns (4,5) P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3) . PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Participates in cellular signaling in response to various growth factors.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Innovating Scientists Reward

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Reconsitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-1:2000
IHC 1:100-1:500
ICC/IF 1:50-1:200
FC 1:500

Validation Images & Assay Conditions

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All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.

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All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.

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All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.

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All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.

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All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.

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All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.

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Western blot analysis of p63 expression in A431 cell lysate.

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Immunohistochemical analysis of paraffin-embedded Human thyroid cancer, using the Antibody at 1:500 dilution.

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Immunohistochemical analysis of paraffin-embedded Human prostate cancer, using the Antibody at 1:500 dilution.

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Immunohistochemical analysis of paraffin-embedded Human small cell lung cancer , using the Antibody at 1:500 dilution.

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Immunohistochemical analysis of paraffin-embedded human breast, using p63 Antibody.

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Immunofluorescent analysis of A431 cells, using p63 Antibody.

Gene/Protein Information For TP63 (Source: Uniprot.org, NCBI)

Alternative Names

amplified in squamous cell carcinoma; Chronic ulcerative stomatitis protein; CUSP; EEC3; EEC3B(p51B); Keratinocyte transcription factor KET; KET; KETRHS; LMS; OFC8; OFC8SHFM4TP73LNBP; p40; p51; p51tumor protein p53-like; p53CP; p63; p63AIS; p73H; p73L; p73LB(p51A); SHFM4; TP53CP; TP53L; TP63; TP73L; Transformation-related protein 63; tumor protein 63; tumor protein p53-competing protein; tumor protein p63 deltaN isoform delta; tumor protein p63; Tumor protein p73-like TP63 AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L tumor protein p63 tumor protein 63|amplified in squamous cell carcinoma|chronic ulcerative stomatitis protein|keratinocyte transcription factor KET|transformation-related protein 63|tumor protein p53-competing protein

For more info on TP63, check out the TP63 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for TP63: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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