Anti-PACS2 Antibody

Product Name

Anti-PACS2 Antibody

View all PACS2 Antibodies

SKU/Catalog Number

A08193

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-PACS2 Antibody (Catalog # A08193). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

PACS2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Cite This Product

Anti-PACS2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08193)

Host

Rabbit

Contents

PACS2 antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

PACS2 antibody was raised against a 17 amino acid peptide near the center of human PACS2. The immunogen is located within amino acids 330 - 380 of PACS2.

Cross-reactivity

PACS2 antibody is human, mouse and rat reactive. At least three isoforms of PACS2 are known to exist; this antibody will detect all three. PACS2 antibody is predicted to not cross-react with PACS1.

Reactive Species

A08193 is reactive to PACS2 in Human, Mouse, Rat

Observed Molecular Weight

68 kDa

Calculated molecular weight

97.7 kDa

Background of PACS2

PACS2 (phosphofurin acidic cluster sorting protein-2), PACS1L, is an 889 amino acid protein that localizes to both the mitochondrion and the lumen of the endoplasmic reticulum (ER) and belongs to the PACS family (1,2). It is expressed in a broad range of tissues with highest expression in skeletal muscle, brain, heart, testis and pancreas (2,). PACS2 interacts with Polycystin-2 and BID and functions as a sorting protein that regulates mitochondria-ER communication and is thought to be involved in ion channel trafficking, specifically direct cluster-containing ion channels to distinct subcellular compartments (3-5).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A08193 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

PACS2 antibody can be used for detection of PACS2 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information PACS2

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