Anti-PD1/Pdcd1 Antibody Picoband™

PD-1 antibody

Boster Bio Anti-PD1/Pdcd1 Antibody Picoband™ catalog # A00178-3. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat.

Product Info Summary

SKU: A00178-3
Size: 100 μg/vial
Reactive Species: Mouse, Rat
Host: Rabbit
Application: ELISA, IHC, WB

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Product Name

Anti-PD1/Pdcd1 Antibody Picoband™

View all PD-1 Antibodies

SKU/Catalog Number

A00178-3

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-PD1/Pdcd1 Antibody Picoband™ catalog # A00178-3. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat.

Storage & Handling

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Cite This Product

Anti-PD1/Pdcd1 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00178-3)

Host

Rabbit

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived mouse PD1/Pdcd1 recombinant protein (Position: A48-L288).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A00178-3 is reactive to Pdcd1 in Mouse, Rat

Applications

A00178-3 is guaranteed for ELISA, IHC, WB Boster Guarantee

Background of PD-1

PDCD1 (Programmed cell death 1), also called PD1, encodes a cell surface receptor that is a member of the B7 superfamily involved in immunomodulation. This gene is mapped to 2q37.3. PDCD1 acts as an inhibitory molecule on T cells after interacting with its ligands PDL1 and PDL2. The PDCD1 gene contains 5 exons. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. Using flow cytometric analysis, it has been found that expression of PDCD1 was upregulated on CD16-positive and CD16-negative monocytes, but not on dendritic cells, in viremic HIV-positive patients, but not in highly active antiretroviral therapy (HAART)-treated HIV-positive patients. PDCD1 upregulation in monocytes was induced by microbial Toll-like receptor ligands and inflammatory cytokines.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Reconsitution

Adding 0.2 ml of distilled water will yield a concentration of 500 µg/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Western blot, 0.25-0.5 µg/ml, Mouse
Immunohistochemistry(Paraffin-embedded Section), 2-5 µg/ml, Mouse, Rat
Direct ELISA, 0.1-0.5 µg/ml, Mouse

Validation Images & Assay Conditions

Gene/Protein Information For Pdcd1 (Source: Uniprot.org, NCBI)

Uniprot ID

Q02242

Gene ID

18566

Gene Name

Pdcd1

Full Name

Programmed cell death protein 1

Weight

31.842kDa

Alternative Names

CD279 antigen; CD279; hPD-1; PD1; PD-1; PD1hPD-l; PDCD1; programmed cell death 1; programmed cell death protein 1; Protein PD-1; SLEB2 Pdcd1|Ly101, PD-, PD-1, Pdc, Pdc1|programmed cell death 1|programmed cell death protein 1|mPD-1|programmed cell death 1 protein|protein PD-1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on Pdcd1, check out the Pdcd1 Infographic

Pdcd1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for Pdcd1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]

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Size

Conjugation

Total: $315

SKU:A00178-3

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Ships directly to USA and Canada. For other regions, visit our distributors page

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A00178-3
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$315.00

$50 fee for conjugation. Antibody size is reduced to 50ug.

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