Many biological assays use antibodies to detect PDCD1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PDCD1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PDCD1 antibodies...
We validate the specificity of these antibodies to PDCD1 by testing them on tissues known to express PDCD1 positively and negatively. Browse below to find the PDCD1 antibody that suites your experiment. We have 65 of these antibodies and many publications and validation images.
If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.
Inhibitory cell surface receptor involved in the regulation of T-cell function during tolerance and immunity. Upon ligand binding, inhibits T-cell effector functions in an antigen- specific manner.
Potential cell death inducer, in association with other elements. .
Gene Information
Human
Gene Name:
PDCD1
Uniprot:
Q15116
Entrez:
5133
Family
Belongs to:
No superfamily
Alternative Names
CD279 antigen; CD279; hPD-1; PD1; PD-1; PD1hPD-l; PDCD1; programmed cell death 1; programmed cell death protein 1; Protein PD-1; SLEB2
Cell membrane; Single-pass type I membrane protein.
Diseases
Neoplasms
Autoimmune Reaction
Autoimmune Diseases
Virus Diseases
Malignant Neoplasms
Hiv Infections
Infective Disorder
Hepatitis
Exhaustion
Lupus Erythematosus, Systemic
Autoimmunity
Hepatitis B
Hepatitis, Chronic
Inflammation
Lymphoma
Hepatitis C
Decreased Immunologic Activity [pe]
Hepatitis B, Chronic
Hepatitis C, Chronic
Diabetes Mellitus
Interacting Proteins
CD274
PDCD1LG2
PTPN11
Pathways
Cell Death
Cell Activation
Immune Response
Programmed Cell Death
T Cell Activation
Cytokine Production
Cell Proliferation
Pathogenesis
Secretion
T Cell Proliferation
Cytokine Secretion
Viral Replication
Cell Differentiation
Lymphocyte Activation
Inflammatory Response
Senescence
Tolerance Induction
Hypersensitivity
Localization
Adaptive Immune Response
PTMs
Phosphorylation
Demethylation
Methylation
Glycosylation
Dephosphorylation
For details, visit: bosterbio.com/bosterbio-gene-info-cards/PDCD1
References
PMID: 7851902 by Shinohara T., et al. Structure and chromosomal localization of the human PD-1 gene (PDCD1).
PMID: 9332365 by Finger L.R., et al. The human PD-1 gene: complete cDNA, genomic organization, and developmentally regulated expression in B cell progenitors.
7 Publications of Boster PDCD1 Antibodies & ELISA Kits
PubMed ID: 10.1007/s10753-018-0754-2, Mycophenolate Mofetil Protects Septic Mice via the Dual Inhibition of Inflammato...